What is the recommended treatment for a stye (hordeolum)?

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Last updated: December 8, 2025View editorial policy

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Treatment for Stye (Hordeolum)

Warm compresses applied for 5-10 minutes once or twice daily, followed by gentle eyelid cleansing and massage, is the first-line treatment for styes. 1, 2

First-Line Conservative Management

The cornerstone of stye treatment is conservative therapy with warm compresses and eyelid hygiene:

  • Apply warm compresses to the affected eyelid for 5-10 minutes to soften debris and warm the meibomian secretions 1, 2
  • Perform this once or twice daily at times convenient for the patient 1, 2
  • Use hot tap water on a clean washcloth, over-the-counter heat packs, or homemade bean/rice bags heated in a microwave for sustained warmth 1, 2
  • Ensure the compress is warm but not hot enough to burn the skin 1

After warm compresses, perform gentle eyelid cleansing and massage to help express the contents of the affected gland 1, 2:

  • Gently rub the base of the eyelashes using diluted baby shampoo or commercially available eyelid cleaner on a cotton ball, cotton swab, or clean fingertip 1, 2
  • Eye cleaners containing hypochlorous acid at 0.01% have strong antimicrobial effects and can be used 1, 2
  • Regular eyelid cleansing performed daily or several times weekly often reduces symptoms 2

Second-Line Antibiotic Therapy

For moderate to severe cases that don't respond to warm compresses and eyelid hygiene alone, add topical antibiotic ointment 1, 2:

  • Apply bacitracin or erythromycin ointment to the eyelid margins once or more daily or at bedtime for a few weeks 1, 2
  • Topical antibiotics provide symptomatic relief and decrease bacteria from the eyelid margin 1, 2
  • The frequency and duration should be guided by severity and response to treatment 1

It's worth noting that a 2017 Cochrane review found no randomized controlled trials evaluating non-surgical interventions for acute internal hordeolum 3, meaning current recommendations are based on expert consensus rather than high-quality evidence. However, the American Academy of Ophthalmology guidelines strongly support this approach 4.

Important Safety Considerations

Patients must be counseled on proper technique to avoid complications:

  • Patients with neurotrophic corneas need proper counseling to avoid injury to corneal epithelium during eyelid cleansing 1, 2
  • Patients with advanced glaucoma should avoid aggressive pressure on the eyelids as it may increase eye pressure 2
  • Eyelid cleaning can be dangerous if the patient lacks manual dexterity or necessary skill to perform the task safely 1, 2

When to Escalate Care

Consider further evaluation if:

  • The stye is markedly asymmetric, resistant to therapy, or recurrent in the same location - consider biopsy to exclude carcinoma 1, 2
  • Long-term antibiotic treatment may result in development of resistant organisms, so avoid prolonged use 4, 1, 2

Expected Course

Patients should understand that:

  • Many styes drain spontaneously and resolve without treatment 5, 3
  • Warm compress and eyelid cleansing treatment may be required long-term, as symptoms often recur when treatment is discontinued 1, 2
  • A cure is usually not possible for chronic blepharitis, which predisposes to recurrent styes 4

References

Guideline

Treatment for Stye (Hordeolum)

Praxis Medical Insights: Practical Summaries of Clinical Guidelines, 2025

Guideline

Treatment and Prevention for Eye Styes (Hordeolum)

Praxis Medical Insights: Practical Summaries of Clinical Guidelines, 2025

Research

Non-surgical interventions for acute internal hordeolum.

The Cochrane database of systematic reviews, 2017

Guideline

Guideline Directed Topic Overview

Dr.Oracle Medical Advisory Board & Editors, 2025

Research

Interventions for acute internal hordeolum.

The Cochrane database of systematic reviews, 2013

Professional Medical Disclaimer

This information is intended for healthcare professionals. Any medical decision-making should rely on clinical judgment and independently verified information. The content provided herein does not replace professional discretion and should be considered supplementary to established clinical guidelines. Healthcare providers should verify all information against primary literature and current practice standards before application in patient care. Dr.Oracle assumes no liability for clinical decisions based on this content.

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