Can the Measles, Mumps, and Rubella (MMR) vaccine and Influenza (flu) vaccine be administered together to a 6-month-old infant?

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Last updated: December 8, 2025View editorial policy

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MMR and Influenza Vaccine Cannot Be Given Together to a 6-Month-Old

The MMR vaccine should not be administered to a 6-month-old infant because the minimum age for MMR vaccination is 12 months. However, the influenza vaccine can and should be given starting at 6 months of age. 1, 2

Why MMR Cannot Be Given at 6 Months

  • The minimum age for MMR vaccination is 12 months, as established by both the American Academy of Pediatrics and the Centers for Disease Control and Prevention. 1, 2
  • The first dose should be administered between 12-15 months of age as part of routine childhood immunization. 1
  • Administering MMR before 12 months is outside the approved age range and not recommended for routine use. 2, 3

Influenza Vaccine at 6 Months

  • Influenza vaccine is specifically recommended starting at 6 months of age. 2, 4
  • All children aged 6-59 months should receive influenza vaccine annually. 2
  • For children younger than 8 years receiving influenza vaccine for the first time, two doses separated by at least 4 weeks are required. 2
  • The appropriate dosage for a 6-month-old is 0.25 mL of trivalent inactivated influenza vaccine. 2

When Both Vaccines Can Be Given Together

Once the child reaches 12 months of age, MMR and influenza vaccines can be safely administered simultaneously. 5, 6

  • The Advisory Committee on Immunization Practices explicitly recommends simultaneous administration of all vaccines for which a person is eligible, including live vaccines like MMR and inactivated vaccines like influenza. 5
  • Each vaccine should be given at a different anatomical site (different limbs). 5
  • Concurrent administration provides equivalent immunogenicity compared to separate administration and is well tolerated. 6
  • There is no medical reason to separate these vaccines when both are due. 5

Common Pitfall to Avoid

Do not confuse the hepatitis B vaccine (which is given at birth) with other vaccines. Healthcare providers have inadvertently administered influenza vaccine to newborns due to confusion with the birth dose of hepatitis B vaccine. 7 Always verify the patient's age and the specific vaccine being administered before proceeding.

Professional Medical Disclaimer

This information is intended for healthcare professionals. Any medical decision-making should rely on clinical judgment and independently verified information. The content provided herein does not replace professional discretion and should be considered supplementary to established clinical guidelines. Healthcare providers should verify all information against primary literature and current practice standards before application in patient care. Dr.Oracle assumes no liability for clinical decisions based on this content.

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