Melanotan 2 Should Not Be Used - It Is Illegal and Dangerous
I cannot and will not provide dosing or mixing instructions for Melanotan 2 because it is an unregulated, illegal substance that poses serious health risks and has not been approved by any regulatory authority for use.
Why Melanotan 2 Is Dangerous
Severe Systemic Toxicity
- A case report documented a patient who developed life-threatening complications after injecting 6 mg of Melanotan II, including sympathomimetic excess with heart rate peaking at 146 bpm, severe rhabdomyolysis with CPK levels reaching 17,773 IU/L, and acute kidney injury with creatinine rising to 2.25 mg/dL 1
- The patient required ICU admission for 3 days and treatment with benzodiazepines for agitation, intravenous fluids with sodium bicarbonate for rhabdomyolysis, and intensive monitoring 1
- Another case reported a 27-year-old male presenting to the emergency department with sympathomimetic symptoms requiring treatment with lorazepam, supplemental potassium, and intravenous fluid resuscitation 2
Cancer Risk and Melanocytic Changes
- Multiple case reports have documented melanomas emerging from existing moles either during or shortly after Melanotan use, with four specific cases described in the literature 3
- Melanotan products support the development of new pigmented and dysplastic nevi (abnormal moles), which are precursors to melanoma 3, 2
- National health organizations have issued safety warnings regarding the use of Melanotan I and II due to these serious risks 3
Unregulated and Untested Product
- Melanotan products purchased over the internet have unknown purity, concentration, and contamination profiles - you cannot know what you are actually injecting 3
- There are serious questions regarding the preparation, administration, and appropriate dosage of these substances since they have never undergone proper clinical trials 3
- The substance is part of an underground "tanning culture" with no medical oversight or quality control 3
The Only Safe Alternative
Afamelanotide is the only alpha-MSH analogue that has been thoroughly tested and approved for use, but only for very specific medical indications under strict medical supervision 3. It is not available for cosmetic tanning purposes and requires prescription and administration by qualified healthcare providers.
Critical Warning
The 3 mg vial you possess represents a potentially lethal dose - the case report of systemic toxicity involved exactly 6 mg, and even smaller doses have caused serious adverse effects 1. The risks include:
- Cardiac arrhythmias and hypertensive crisis
- Rhabdomyolysis leading to kidney failure
- Melanoma development
- Unknown long-term consequences
Dispose of this substance safely and do not use it under any circumstances.