What is the treatment for paronychia?

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Treatment of Paronychia

Treat paronychia based on severity grading: mild cases respond to warm soaks and topical steroids, moderate cases require oral antibiotics, and severe cases with abscess formation mandate surgical drainage. 1, 2

Initial Assessment

Evaluate severity using these parameters to guide treatment decisions 1, 2:

  • Redness, edema, discharge, and granulation tissue presence 1
  • Check specifically for pus or abscess formation - this finding changes management from conservative to surgical 1, 2
  • Identify predisposing factors including ingrown toenails, occupational water exposure, or medication-induced causes 2

Treatment Algorithm by Severity

Grade 1 (Mild) Paronychia

Start with antiseptic soaks and topical anti-inflammatory therapy 1, 2:

  • Warm water soaks for 15 minutes 3-4 times daily OR white vinegar soaks (1:1 white vinegar:water ratio) for 15 minutes daily 1, 3
  • Apply topical 2% povidone-iodine twice daily to the affected area 1, 3
  • Use mid to high potency topical steroid ointment to nail folds twice daily to reduce inflammation 1, 3

Grade 2 (Moderate) Paronychia

Escalate to systemic antibiotics when signs of infection are present 1, 2:

  • Start oral antibiotics: preferred agents are cephalexin or amoxicillin-clavulanate (Augmentin 500/125 mg every 12 hours) 2, 3
  • If cephalexin fails, switch to sulfamethoxazole-trimethoprim (Bactrim) for broader coverage including MRSA 3
  • Avoid clindamycin - it lacks adequate streptococcal coverage and has increasing resistance patterns 3
  • Continue topical very potent steroids, antifungals, antibiotics and/or antiseptics (preferably as combination preparations) 1, 2

Grade 3 (Severe) Paronychia

Surgical drainage is mandatory when abscess is present 1, 2:

  • Swab any pus for culture before starting antibiotics 1, 3
  • Perform surgical drainage - options range from instrumentation with hypodermic needle to wide incision with scalpel 1, 4
  • Prescribe appropriate antibiotics based on culture results 3
  • Oral antibiotics are usually not needed if adequate drainage is achieved, unless the patient is immunocompromised or severe infection is present 3, 4

Chronic Paronychia Management

High-potency topical corticosteroids are more effective than antifungals for chronic paronychia and should be first-line treatment 1, 2, 5:

  • Apply high-potency topical corticosteroids as primary therapy 1, 5
  • Consider intralesional triamcinolone acetonide for recalcitrant cases 1
  • Topical timolol 0.5% gel twice daily under occlusion has shown benefit in some cases 1
  • Regular application of emollients to cuticles and periungual tissues 2
  • Identify and eliminate irritants - common culprits include acids, alkalis, and chemicals used by housekeepers, dishwashers, bartenders, florists, bakers, and swimmers 4

Critical Pitfall to Avoid

Do not overlook secondary bacterial or mycological superinfections, which are present in up to 25% of cases 1, 3:

  • Obtain bacterial cultures before starting antibiotics, especially in severe cases or treatment failures 3
  • Mixed infections with bacteria, fungus, and yeast are common in chronic paronychia 6

Prevention of Recurrence

Implement these measures to prevent recurrence 1, 2:

  • Keep hands and feet as dry as possible - avoid prolonged soaking in water 1, 2
  • Avoid nail trauma/injury and cutting nails too short 1, 2
  • Moisturize hands and feet regularly with emollients applied to cuticles and periungual tissues 1, 2
  • Wear protective gloves during wet work or exposure to irritants 1, 2
  • Wear comfortable well-fitting shoes that protect nails without being restrictive 1, 2

Follow-up Protocol

Reassess after 2 weeks of treatment 1, 3:

  • If no improvement is seen, refer to dermatology or podiatry for further evaluation 1, 3
  • Treatment for chronic paronychia may take weeks to months 4

References

Guideline

Treatment of Paronychia

Praxis Medical Insights: Practical Summaries of Clinical Guidelines, 2025

Guideline

Paronychia Treatment Guidelines

Praxis Medical Insights: Practical Summaries of Clinical Guidelines, 2025

Guideline

Treatment of Acute Paronychia

Praxis Medical Insights: Practical Summaries of Clinical Guidelines, 2025

Research

Acute and Chronic Paronychia.

American family physician, 2017

Research

Management of chronic paronychia.

Indian journal of dermatology, 2014

Research

Paronychia.

Clinics in podiatric medicine and surgery, 1995

Professional Medical Disclaimer

This information is intended for healthcare professionals. Any medical decision-making should rely on clinical judgment and independently verified information. The content provided herein does not replace professional discretion and should be considered supplementary to established clinical guidelines. Healthcare providers should verify all information against primary literature and current practice standards before application in patient care. Dr.Oracle assumes no liability for clinical decisions based on this content.

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