Differential Diagnosis for Autoimmune Disease with Diffuse Abdominal Pain, Bloating, and Migraines
- Single Most Likely Diagnosis
- Systemic Lupus Erythematosus (SLE): This is a likely diagnosis due to its potential to cause a wide range of symptoms including diffuse abdominal pain, bloating, and migraines, in addition to its autoimmune nature.
- Other Likely Diagnoses
- Rheumatoid Arthritis (RA): Although primarily known for joint symptoms, RA can also cause systemic symptoms including abdominal issues and headaches.
- Sjögren's Syndrome: This autoimmune disorder can cause a variety of symptoms including abdominal pain and headaches, often in conjunction with its hallmark symptoms of dry eyes and mouth.
- Hashimoto's Thyroiditis: While primarily affecting the thyroid, Hashimoto's can lead to a range of systemic symptoms including abdominal discomfort and migraines.
- Do Not Miss Diagnoses
- Vasculitis (e.g., Polyarteritis Nodosa): These conditions can cause severe abdominal pain and systemic symptoms, and missing them could lead to serious complications or death.
- Autoimmune Hepatitis: Although less common, this condition can present with abdominal pain and systemic symptoms, and early diagnosis is crucial for effective treatment.
- Rare Diagnoses
- Ehlers-Danlos Syndrome: A group of disorders that affect connective tissues, which can lead to a variety of symptoms including abdominal issues and migraines, though it's more known for its effects on skin, joints, and blood vessels.
- Mast Cell Activation Syndrome: A condition that can cause a wide range of symptoms including abdominal pain, bloating, and migraines due to the abnormal release of histamine and other mediators from mast cells.