What are the recommended health screenings for a 65-year-old male?

Medical Advisory BoardAll articles are reviewed for accuracy by our Medical Advisory Board
Educational purpose only • Exercise caution as content is pending human review
Article Review Status
Submitted
Under Review
Approved

Last updated: December 9, 2025View editorial policy

Personalize

Help us tailor your experience

Which best describes you? Your choice helps us use language that's most understandable for you.

Recommended Health Screenings for a 65-Year-Old Male

A 65-year-old male should undergo colorectal cancer screening (colonoscopy every 10 years or annual FIT testing), biennial abdominal aortic aneurysm ultrasound if he has ever smoked, lipid screening every 5 years, blood pressure monitoring, diabetes screening, and informed decision-making discussion about prostate cancer screening if he has at least 10 years life expectancy. 1

Cancer Screenings

Colorectal Cancer Screening

  • Begin or continue regular colorectal cancer screening with one of the following options 1:
    • Annual fecal immunochemical test (FIT) 1
    • Annual high-sensitivity guaiac-based fecal occult blood test (HSgFOBT) 1
    • Multitarget stool DNA test every 3 years 1
    • Colonoscopy every 10 years 1
    • CT colonography every 5 years 1
    • Flexible sigmoidoscopy every 5 years 1
  • All positive non-colonoscopy tests must be followed with timely colonoscopy 1
  • Continue screening through age 75 if in good health with life expectancy >10 years 1

Prostate Cancer Screening

  • Engage in shared decision-making about PSA testing if life expectancy is at least 10 years 1, 2
  • The discussion should include potential benefits (mortality reduction), harms (overdiagnosis, biopsy complications), and uncertainties 1
  • PSA screening should not occur without an informed decision-making process 1
  • At age 65, screening decisions depend heavily on overall health status and comorbidities 1

Common Pitfall: Many clinicians either reflexively order PSA tests without informed consent or completely avoid the discussion. The guideline-recommended approach is to have a structured conversation about the trade-offs, then proceed based on the patient's informed preference 1, 2.

Lung Cancer Screening

  • Low-dose helical CT annually if the patient 1:
    • Currently smokes or quit within the past 15 years, AND
    • Has at least a 30 pack-year smoking history, AND
    • Is in good health
  • Must include smoking cessation counseling for current smokers 1
  • Requires access to a high-volume, high-quality screening and treatment center 1

Cardiovascular Screenings

Lipid Screening

  • Screen with total cholesterol and HDL cholesterol (non-fasting acceptable) 3
  • Repeat every 5 years if normal; more frequently if borderline 3
  • Confirm all abnormal results with repeat testing before diagnosis 3
  • Lipid disorders remain highly relevant at age 65, with prevalence of dyslipidemia at 60.3% in this age group 4

Blood Pressure Monitoring

  • Regular blood pressure screening is essential, as hypertension prevalence reaches 63-77% in adults ≥65 years 4
  • Control rates remain suboptimal (approximately 49% among those treated) 4

Diabetes Screening

  • Screen for diabetes, particularly given the 21.2% prevalence in older adults 4
  • Diabetes is a modifiable risk factor strongly associated with cardiovascular outcomes in the elderly 5, 6

Abdominal Aortic Aneurysm (AAA) Screening

  • One-time ultrasound screening for AAA if the patient has ever smoked 3
  • This is a critical screening often overlooked in 65-year-old males with smoking history

Additional Considerations

Bone Health

  • Assess fracture risk and consider bone density screening if risk factors are present 1
  • Supplemental calcium (1200 mg/day) and vitamin D3 (800-1000 IU/day) recommended for all men >50 years 1

Behavioral Risk Factors

  • Physical activity, smoking cessation, and weight management are modifiable factors strongly associated with healthy aging 5
  • These behavioral interventions remain significant predictors of health even after controlling for other cardiovascular risk factors 5

Critical Pitfall: Clinicians often assume that preventive measures are less valuable in older adults. However, the absolute risk reduction is actually greater in the elderly due to higher baseline risk, making screening and risk factor modification more impactful in terms of lives saved per number screened 7, 6.

References

Guideline

Guideline Directed Topic Overview

Dr.Oracle Medical Advisory Board & Editors, 2025

Guideline

Age Recommendations for PSA Screening Initiation in Prostate Cancer

Praxis Medical Insights: Practical Summaries of Clinical Guidelines, 2025

Guideline

Health Screenings for a 45-Year-Old Male

Praxis Medical Insights: Practical Summaries of Clinical Guidelines, 2025

Research

Prevalence, awareness, and management of hypertension, dyslipidemia, and diabetes among United States adults aged 65 and older.

The journals of gerontology. Series A, Biological sciences and medical sciences, 2009

Research

Factors associated with healthy aging: the cardiovascular health study.

Journal of the American Geriatrics Society, 2001

Research

The Importance of Cardiovascular Risk Factors in the Elderly.

The American journal of geriatric cardiology, 1995

Professional Medical Disclaimer

This information is intended for healthcare professionals. Any medical decision-making should rely on clinical judgment and independently verified information. The content provided herein does not replace professional discretion and should be considered supplementary to established clinical guidelines. Healthcare providers should verify all information against primary literature and current practice standards before application in patient care. Dr.Oracle assumes no liability for clinical decisions based on this content.

Have a follow-up question?

Our Medical A.I. is used by practicing medical doctors at top research institutions around the world. Ask any follow up question and get world-class guideline-backed answers instantly.