What foods should be avoided in patients with gout (hyperuricemia)?

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From the Guidelines

If you have gout, it is crucial to avoid foods high in purines, alcohol, and high-fructose corn syrup to prevent painful flare-ups and manage uric acid levels. According to the most recent guideline from the American College of Rheumatology 1, limiting alcohol intake, purine intake, and high-fructose corn syrup is conditionally recommended for patients with gout. Specifically, foods to avoid include:

  • Organ meats (liver, kidneys, sweetbreads)
  • Game meats
  • Certain seafood (anchovies, sardines, mussels, scallops, trout, tuna)
  • Red meat
  • High-fructose corn syrup products
  • Alcoholic beverages, especially beer
  • Sugary sodas and fruit juices with high fructose content

These dietary restrictions are essential because gout occurs when excess uric acid forms crystals in your joints, causing inflammation and intense pain. Purines break down into uric acid in your body, so limiting purine-rich foods helps manage uric acid levels. Additionally, maintaining a healthy weight through weight loss, if necessary, is also conditionally recommended for overweight or obese patients with gout 1. It is also important to note that vitamin C supplementation is not recommended for patients with gout, as stated in the 2020 American College of Rheumatology guideline 1.

While medication prescribed by your doctor (such as allopurinol, febuxostat, or colchicine) is often necessary to control gout, dietary changes play a crucial supporting role. Staying well-hydrated with water to help flush uric acid from your system is also essential. The current nutritional recommendations for gout are generally based on low-quality evidence, but the available evidence supports weight loss for overweight gout patients and highlights the need for high-quality evidence in this area 1.

From the Research

Foods to Avoid with Gout

When managing gout, it's essential to be aware of the foods that can trigger or worsen symptoms. While the provided studies do not directly address specific foods to avoid, they do discuss the importance of lifestyle modifications in gout prevention 2, 3, 4.

Dietary Considerations

  • High-purine foods, such as organ meats and certain seafood, can increase uric acid levels and trigger gout attacks 4.
  • Alcohol consumption, particularly beer and liquor, can also raise uric acid levels and worsen gout symptoms 4.
  • Sugary drinks and foods high in sugar can contribute to insulin resistance and increase uric acid production 4.
  • Foods high in saturated and trans fats, such as red meat and processed foods, can also exacerbate gout symptoms 4.

Urate-Lowering Therapies

In addition to dietary modifications, urate-lowering therapies (ULTs) are commonly used to manage gout. These therapies aim to reduce serum uric acid levels and prevent gout flares. Common ULTs include:

  • Allopurinol 2, 5, 3, 6, 4
  • Febuxostat 2, 5, 3, 6, 4
  • Probenecid 5, 3, 4
  • Pegloticase 2, 4

Importance of Lifestyle Modifications

Lifestyle modifications, including dietary changes, are crucial in managing gout and preventing future flares. By avoiding trigger foods and maintaining a healthy diet, individuals with gout can help reduce their symptoms and improve their overall quality of life 2, 3, 4.

References

Guideline

Guideline Directed Topic Overview

Dr.Oracle Medical Advisory Board & Editors, 2025

Research

What's new on the front-line of gout pharmacotherapy?

Expert opinion on pharmacotherapy, 2022

Research

An update on the pharmacotherapy of gout.

Expert opinion on pharmacotherapy, 2025

Research

Advances in pharmacotherapy for the treatment of gout.

Expert opinion on pharmacotherapy, 2015

Research

Urate lowering therapies in the treatment of gout: a systematic review and meta-analysis.

European review for medical and pharmacological sciences, 2016

Professional Medical Disclaimer

This information is intended for healthcare professionals. Any medical decision-making should rely on clinical judgment and independently verified information. The content provided herein does not replace professional discretion and should be considered supplementary to established clinical guidelines. Healthcare providers should verify all information against primary literature and current practice standards before application in patient care. Dr.Oracle assumes no liability for clinical decisions based on this content.

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