Recommended Daily Dosage of ProT Gold for Wound Support
Consume ProT Gold twice daily (morning and evening) to provide the 1.25-1.5 g protein/kg/day recommended for wound healing, which translates to approximately 2-3 shots per day for most adults depending on body weight. 1, 2
Protein Requirements for Wound Healing
The American College of Physicians guidelines establish that patients with pressure injuries who are malnourished or at risk require 1.25-1.5 g protein/kg/day to support wound healing. 1, 2 This recommendation is based on moderate-quality evidence showing protein supplementation reduces wound size and accelerates healing. 1
Critical evidence from prospective wound studies demonstrates that traditional protein estimates are too low: patients with wounds required an average of 1.85 g/kg/day of protein for pre-albumin improvement, significantly higher than the 1.47 g/kg/day needed by non-wound patients. 3 Higher wound burden correlated with increased protein requirements. 3
Calculating Your Specific Dosage
Each ProT Gold shot provides 17g of collagen protein. To determine your daily requirement:
- For a 70 kg (154 lb) patient: 1.25-1.5 g/kg/day = 87.5-105g protein daily
- ProT Gold contribution: 2 shots = 34g collagen protein, 3 shots = 51g collagen protein
- Remaining protein should come from regular dietary sources 1
Most patients will require 2-3 shots daily distributed throughout the day (morning, midday, evening) to meet the enhanced protein demands of wound healing while maintaining dietary protein intake. 1, 3
Evidence Supporting Collagen Supplementation
Hydrolyzed collagen supplementation in burn patients significantly improved wound healing (Hazard ratio 3.7, P=0.007) and serum pre-albumin levels compared to isocaloric placebo. 4 The collagen group showed pre-albumin increases of 13.9 mg/dL at week 2 versus -1.9 mg/dL in controls (P<0.001). 4
Collagen plays critical roles in wound healing by attracting fibroblasts, encouraging new collagen formation in the wound bed, and serving as a key component of the extracellular matrix. 5, 6 Hydroxyproline, unique to collagen, serves as an ideal marker for collagen synthesis in healing wounds. 7
Timing and Administration Strategy
- Distribute doses throughout the day rather than consuming all at once to maintain steady amino acid availability for tissue repair 1
- Continue supplementation for minimum 4 weeks based on clinical trial evidence showing significant improvements at this timepoint 4
- Monitor pre-albumin levels every 2 weeks to assess protein status and adjust intake accordingly 3, 4
Additional Nutritional Considerations
Combine collagen supplementation with:
- Total caloric intake of 30-35 kcal/kg/day to prevent protein catabolism for energy 1, 2
- Adequate hydration to improve microvascular perfusion 1, 2
- Micronutrient supplementation including arginine (2g per shot in ProT Gold), zinc, B vitamins, and glutamate 1, 2
Do not rely on vitamin C or vitamin D supplementation unless documented deficiency exists, as evidence does not support routine supplementation for wound healing. 1, 8
Critical Pitfalls to Avoid
- Do not underdose protein - traditional estimates of 0.8-1.0 g/kg/day are insufficient for wound patients 3
- Do not delay supplementation - protein deficiency impedes wound healing and increases infection risk 1
- Do not ignore signs of inadequate protein provision - failure to improve pre-albumin levels within 4 weeks indicates insufficient protein intake or assimilation 3
- Do not exceed 1.85 g/kg/day without monitoring - while no toxicity was observed in studies, this represents the upper range of effective dosing 3