Can Triazepide Cause Low Blood Pressure?
I cannot find any medication called "Trizepiyide" or "Triazepide" in the provided evidence or in standard medical references. This appears to be either a misspelling, a regional/brand name not in common use, or a non-existent medication.
Possible Interpretations
If you are asking about a medication that causes low blood pressure, consider whether you meant one of these commonly confused drug names:
Thiazide Diuretics (most likely intended medication)
- Thiazide diuretics definitively cause low blood pressure—this is their primary therapeutic mechanism of action 1, 2.
- Thiazides lower blood pressure in a dose-dependent manner, with hydrochlorothiazide at 25 mg/day reducing blood pressure by 8/3 mmHg compared to placebo 2.
- Thiazides can cause postural hypotension (orthostatic hypotension), particularly with excessive diuresis or sudden volume loss 3.
- The blood pressure-lowering effect occurs through initial volume depletion of approximately 2 liters of extracellular fluid, followed by long-term reduction in total peripheral vascular resistance 1.
- Hypovolemia and postural hypotension are recognized adverse effects, especially in elderly patients with poor mobility 4.
Other Medications That Cause Hypotension
If you meant a different medication, here are drugs with similar-sounding names that cause low blood pressure:
- Antipsychotics (if you meant medications ending in "-azine"): Chlorpromazine, methotrimeprazine, and quetiapine all cause orthostatic hypotension 4.
- Calcium channel blockers: Both dihydropyridines and non-dihydropyridines cause hypotension and falls 4.
- Tricyclic antidepressants: Associated with orthostatic hypotension 3, 5.
Recommendation
Please verify the exact spelling and generic name of the medication in question. Check the medication label, prescription, or packaging to confirm the correct name, as I cannot provide specific guidance on a medication that does not exist in medical literature or the evidence provided.
If you confirm this is a thiazide diuretic, then yes, it absolutely causes low blood pressure as its intended effect, with orthostatic hypotension being a recognized adverse effect requiring blood pressure monitoring 4, 2.