What is the appropriate management for a primigravida (first-time pregnant woman) at 32 weeks of gestation with mild headache, no abdominal pain or visual disturbance, hypertension (elevated blood pressure), and proteinuria (+3 protein in urine)?

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Management of Preeclampsia at 32 Weeks Gestation

This patient requires immediate hospitalization for close monitoring and stabilization, not delivery at this time (Option B). 1, 2

Clinical Diagnosis

This primigravida presents with preeclampsia without severe features at 32 weeks gestation:

  • Blood pressure 150/90 mmHg (elevated but <160/110 mmHg) 3
  • Significant proteinuria (+3 on dipstick) 3
  • Mild headache only, without visual disturbances, epigastric pain, or other severe features 3, 1

Hospitalization is mandatory for all pregnant women with preeclampsia at the time of diagnosis, regardless of gestational age or severity. 1, 2 This is critical because preeclampsia can rapidly progress to an emergency, and the condition should not be classified as "mild" versus "severe" clinically. 2

Why Not Immediate Delivery?

At 32 weeks gestation, delivery should be delayed to allow for fetal maturation unless severe features develop. 3 The guidelines are clear:

  • Delivery is indicated at ≥37 weeks for any preeclampsia 1, 2
  • At <34 weeks without severe features, expectant management with close monitoring is appropriate 3
  • Immediate delivery (vaginal or cesarean) is reserved for severe preeclampsia with features threatening maternal or fetal wellbeing 3

Inpatient Management Protocol

Blood Pressure Control

  • Initiate oral antihypertensive therapy targeting diastolic BP 85 mmHg and systolic BP 110-140 mmHg 1, 2
  • First-line agents: methyldopa, labetalol, or oral nifedipine 3, 1
  • Monitor BP every 4 hours or more frequently if needed 1, 2

Seizure Prophylaxis

Magnesium sulfate should be administered for seizure prophylaxis given the presence of headache, even though mild. 1, 2 Women with preeclampsia who have symptoms such as headache require magnesium sulfate during labor and for 24 hours postpartum. 1, 4

Maternal Monitoring

  • Clinical evaluation including deep tendon reflexes and clonus 1
  • Laboratory tests at admission and at least twice weekly: hemoglobin, platelets, liver transaminases, creatinine, uric acid 1, 2
  • Watch for alarm signs: severe headache, visual disturbances, epigastric pain, dyspnea 1, 2

Fetal Monitoring

  • Initial cardiotocography and ultrasound for biometry, amniotic fluid, and umbilical artery Doppler 2
  • Corticosteroids for fetal lung maturity should be administered at ≤34 weeks gestation 3

Indications for Immediate Delivery

Delivery should be pursued if any of the following develop:

  • Gestational age reaches 37 weeks 1, 2
  • Blood pressure ≥160/110 mmHg (severe hypertension requiring urgent treatment) 3, 2
  • Signs of maternal organ dysfunction: deteriorating renal function, elevated liver enzymes, low platelets, pulmonary edema 3
  • Neurological symptoms worsen: severe persistent headache, visual disturbances, altered mental status 3, 1
  • Fetal distress or intrauterine growth restriction 3

Common Pitfalls to Avoid

  • Do not attempt outpatient management - all preeclampsia requires hospitalization at diagnosis 1, 2
  • Do not rush to cesarean section - vaginal delivery should be attempted unless obstetric contraindications exist 1, 2
  • Do not withhold magnesium sulfate - headache, even if mild, warrants seizure prophylaxis in preeclampsia 1, 2, 4
  • Do not delay corticosteroids - fetal lung maturity is critical at 32 weeks if preterm delivery becomes necessary 3

The baseline proteinuria at this gestational age significantly increases risk for superimposed complications and adverse outcomes, making close inpatient monitoring essential. 5

References

Guideline

Management of Preeclampsia at 38 Weeks

Praxis Medical Insights: Practical Summaries of Clinical Guidelines, 2025

Guideline

Manejo de Preeclampsia Severa

Praxis Medical Insights: Practical Summaries of Clinical Guidelines, 2025

Guideline

Guideline Directed Topic Overview

Dr.Oracle Medical Advisory Board & Editors, 2025

Professional Medical Disclaimer

This information is intended for healthcare professionals. Any medical decision-making should rely on clinical judgment and independently verified information. The content provided herein does not replace professional discretion and should be considered supplementary to established clinical guidelines. Healthcare providers should verify all information against primary literature and current practice standards before application in patient care. Dr.Oracle assumes no liability for clinical decisions based on this content.

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