Initial Management of Bronchitis
Distinguish Between Acute and Chronic Bronchitis First
The initial approach depends critically on whether you are managing acute bronchitis (self-limited viral infection) or chronic bronchitis (chronic inflammatory condition), as these require fundamentally different management strategies. 1, 2
For Acute Bronchitis
Diagnosis and Assessment
- Diagnose clinically based on history and physical examination alone—do not routinely order laboratory tests or chest radiography. 1, 3
- Rule out pneumonia by checking for vital sign abnormalities: heart rate >100 bpm, respiratory rate >24 breaths/min, oral temperature >38°C, or focal chest examination findings (rales, egophony, tactile fremitus). 1, 3
- If these findings are absent, pneumonia is unlikely and chest x-ray is not needed. 3, 4
- Consider pertussis if cough persists beyond 2-3 weeks with paroxysmal features, whooping, or post-tussive vomiting. 1, 4
Treatment Approach
- Do NOT prescribe antibiotics routinely—they reduce cough duration by only 0.5 days while exposing patients to adverse effects including allergic reactions, gastrointestinal symptoms, and C. difficile infection. 1, 5, 6
- The presence of purulent or colored sputum does NOT indicate bacterial infection and is NOT an indication for antibiotics. 1, 3
- Exception: Prescribe a macrolide antibiotic (erythromycin) if pertussis is confirmed or suspected, and isolate the patient for 5 days from treatment start. 1
Symptomatic Management
- Do NOT routinely prescribe β2-agonist bronchodilators for most patients. 1, 3
- Consider a trial of β2-agonists only in select patients with wheezing accompanying the cough. 1, 3
- Antitussive agents (codeine or dextromethorphan) may provide modest short-term relief for bothersome cough. 1, 2
- Do NOT use systemic corticosteroids, NSAIDs at anti-inflammatory doses, or chest physiotherapy. 1, 2
Patient Education
- Inform patients that cough typically lasts 10-14 days after the visit, even up to 2-3 weeks—this is the most important intervention. 1, 6, 4
- Refer to the condition as a "chest cold" rather than "bronchitis" to reduce antibiotic expectations. 1, 4
- Explain that patient satisfaction depends more on physician-patient communication than whether antibiotics are prescribed. 1
For Chronic Bronchitis (Stable)
Definition and Assessment
- Chronic bronchitis is defined as cough with sputum production on most days for at least 3 months per year for 2 consecutive years. 2, 7
- Assess for risk factors including smoking history, environmental irritants, and severity of airflow obstruction. 2
Management Approach
- Smoking cessation is the cornerstone of therapy—90% of patients experience resolution of cough after quitting. 2
- Prescribe short-acting β-agonists (albuterol) to control bronchospasm and reduce chronic cough. 2
- Offer ipratropium bromide to improve cough symptoms. 2
- Prescribe long-acting β-agonists combined with inhaled corticosteroids for persistent symptoms. 2
For Acute Exacerbations of Chronic Bronchitis (AECB)
When to Treat with Antibiotics
- Reserve antibiotics for patients with at least one cardinal symptom (increased dyspnea, increased sputum production, or increased sputum purulence) AND at least one risk factor. 2, 7
- Risk factors include: age ≥65 years, FEV₁ <50% predicted, ≥4 exacerbations in 12 months, or comorbidities. 7
- Patients with severe COPD associated with chronic bronchitis benefit most from antibiotic therapy. 8, 9
Treatment for AECB
- Administer short-acting β-agonists or anticholinergic bronchodilators during acute exacerbations. 2
- Prescribe antibiotics for moderate severity: newer macrolides, extended-spectrum cephalosporins, or doxycycline. 7
- For severe exacerbations: high-dose amoxicillin/clavulanate or respiratory fluoroquinolones. 10, 7
- Administer a short course (10-15 days) of systemic corticosteroids for acute exacerbations. 2
Common Pitfalls to Avoid
- Do NOT prescribe antibiotics based solely on colored sputum—this does not indicate bacterial infection. 1, 3
- Do NOT fail to distinguish between acute bronchitis and pneumonia—check vital signs and perform chest examination. 2, 3
- Do NOT use expectorants or mucolytics—they lack evidence of benefit. 2, 3
- Do NOT overlook underlying conditions (asthma, COPD, heart failure) that may be exacerbated. 2
- Do NOT use theophylline for acute exacerbations of chronic bronchitis. 2