Treatment of Tonsillar (Peritonsillar) Abscess
The treatment of peritonsillar abscess requires drainage (needle aspiration as first-line), antibiotics effective against Group A streptococcus and oral anaerobes, and supportive care, with most patients managed in the outpatient setting. 1, 2
Immediate Management
Drainage Procedures
- Needle aspiration is the gold standard for both diagnosis and treatment of peritonsillar abscess 3
- Incision and drainage may be required in advanced cases where needle aspiration is inadequate 3
- Drainage combined with antibiotic therapy and hydration are the cornerstones of treatment 2, 4
Antibiotic Selection
- First-line antibiotics must be effective against Group A streptococcus and oral anaerobes 1, 2
- Appropriate antibiotic options include:
- Penicillin (covers streptococcus) 3
- Clindamycin (provides excellent anaerobic coverage and is recommended for children with asthma due to increased complication risk) 1
- Amoxicillin-clavulanate (80 mg/kg/day in three doses, maximum 3 g/day for outpatient management, though anaerobic coverage may not be optimal) 1
- Cephalosporins or metronidazole as alternatives 3
- Duration: 7-10 days, adjusted based on clinical response 1
Adjunctive Therapy
- Corticosteroids may reduce symptoms and speed recovery 4
- Supportive therapy for hydration and pain control is essential 2
Inpatient vs. Outpatient Management
- Most patients can be managed in the outpatient setting 2
- Patients with signs of systemic toxicity or severe symptoms should be considered for inpatient management 5
- Key symptoms warranting closer monitoring include: fever, severe throat pain, dysphagia, trismus, and "hot potato" voice 2
Surgical Considerations: Tonsillectomy
Immediate Tonsillectomy
- Immediate tonsillectomy under general anesthesia can be performed safely and provides dramatic symptom relief within days 6
- This approach ensures adequate drainage, which is critical given the high incidence of anaerobes 6
- May be required in advanced cases not responding to needle aspiration 3
- If proceeding to tonsillectomy, do NOT prescribe perioperative antibiotics (strongly recommended against by the American Academy of Otolaryngology-Head and Neck Surgery) 1
Interval/Elective Tonsillectomy
- Consider tonsillectomy in patients with a history of more than one peritonsillar abscess, even if they don't meet standard frequency criteria for recurrent throat infections 1, 5
- May be considered for patients whose symptomatic episodes do not diminish in frequency over time 5
Important Clinical Pitfalls
Atypical Presentations
- In patients without history of recurrent tonsillitis, especially older adults, consider malignant etiology (squamous cell carcinoma or lymphoma) 7
- If tonsillar hypertrophy persists after treatment, tonsillectomy with histologic examination should be performed for early diagnosis 7
Complications to Monitor
- Airway obstruction 2
- Aspiration 2
- Extension of infection into deep neck tissues 2
- Prompt recognition and treatment initiation are critical to avoid these potentially serious complications 2