How do I obtain Biofreeze (menthol)?

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Last updated: December 10, 2025View editorial policy

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How to Obtain Biofreeze

Biofreeze is an over-the-counter topical analgesic product containing menthol that can be purchased without a prescription at pharmacies, drugstores, online retailers, and through healthcare providers' offices.

Product Information

  • Biofreeze is a commercially available topical menthol gel manufactured by Performance Health Inc., Export, PA 1
  • The standard formulation contains 3.5% menthol as the active ingredient 2
  • Menthol acts as a topical counter-irritant by activating TRPM8 channels, producing a cooling sensation and reducing pain through both peripheral and central analgesic pathways 3, 4

Where to Purchase

  • Retail pharmacies and drugstores: Available on shelves in the pain relief or topical analgesic section without requiring a prescription 5
  • Online retailers: Can be ordered through various e-commerce platforms and the manufacturer's website
  • Healthcare provider offices: Chiropractors, physical therapists, and other practitioners often stock and sell Biofreeze directly to patients 1
  • Medical supply stores: Specialty stores that carry rehabilitation and pain management products

Clinical Applications

  • Biofreeze has demonstrated efficacy for acute low back pain when combined with chiropractic adjustments, showing significant pain reduction after each week of treatment 1
  • The product has shown effectiveness for masticatory myofascial pain syndrome, with improvements in pain scores and mouth opening comparable to superficial heat therapy 2
  • Menthol's mechanism involves counter-irritation by initially stimulating nociceptors and then desensitizing them, while also activating central analgesic pathways 3

Typical Usage Instructions

  • Apply to the affected area 2-3 times daily as needed for pain relief 1, 2
  • The cooling effect is acute and short-lived, requiring repeated applications throughout the day 5
  • No prescription or special authorization is required for purchase or use

Important Considerations

  • At high concentrations, menthol may generate cold allodynia (painful cold sensation) 3
  • The favorable effects are limited to the duration of use, with benefits diminishing after discontinuation 2
  • Menthol is widely recognized as safe for topical use and has been used as a non-opioid pain reliever since ancient times 3, 4

References

Professional Medical Disclaimer

This information is intended for healthcare professionals. Any medical decision-making should rely on clinical judgment and independently verified information. The content provided herein does not replace professional discretion and should be considered supplementary to established clinical guidelines. Healthcare providers should verify all information against primary literature and current practice standards before application in patient care. Dr.Oracle assumes no liability for clinical decisions based on this content.

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