What is a normal and high Exdox (exercise oxygen) score?

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What is an EXDOX Score?

I cannot find any reference to an "EXDOX score" or "Exercise Oxygen score" in the provided evidence or in standard cardiopulmonary exercise testing (CPET) literature.

What You May Be Looking For

Based on the context of exercise and oxygen, you may be referring to one of these established CPET parameters:

Peak VO₂ (Oxygen Consumption)

  • Peak VO₂ represents the highest oxygen uptake obtained during exercise and is the most commonly used measure of exercise capacity 1.
  • Normal values: ≥100% of predicted values (wide range from approximately 80 mL O₂·kg⁻¹·min⁻¹ in young elite athletes to 15 mL O₂·kg⁻¹·min⁻¹ in apparently healthy 80-year-old females) 1.
  • Abnormal/reduced values: <100% predicted, with values <40% predicted indicating severe impairment 1.
  • This parameter is influenced by age, sex, central (cardiovascular/pulmonary) and peripheral (skeletal muscle) function 1.

VE/VCO₂ Slope (Ventilatory Efficiency)

  • Represents the relationship between minute ventilation (VE) and carbon dioxide production (VCO₂), reflecting matching of ventilation and perfusion within the pulmonary system 1.
  • Normal value: <30, with slight increase possible with advanced age 1.
  • High/abnormal value: >34 is an independent predictor of mortality in patients with heart failure, mitral valvular disease, or angina 1.
  • Upper limit of normal: 50 1.

Oxygen Saturation (SpO₂) During Exercise

  • Normal: ≥95% at rest and throughout exercise, should not decrease >5% (absolute value) 1.
  • Abnormal: Desaturation is common in patients with COPD, interstitial lung disease (ILD), and pulmonary arterial hypertension as disease severity advances 1.

O₂ Pulse Trajectory

  • Defined as the ratio between VO₂ (mL O₂·min⁻¹) and heart rate (beats per minute), non-invasively reflecting stroke volume response to exercise 1.
  • Normal response: Continual linear rise throughout exercise with possible plateau approaching maximal exertion 1.
  • Abnormal response: Decreased or plateauing early in the test suggests heart failure or ischemic heart disease 1.

Recommendation

If you are asking about exercise oxygen parameters, clarify which specific CPET variable you need information about, as there is no standardized "EXDOX score" in clinical practice. The most relevant parameters for assessing exercise capacity and oxygen utilization are peak VO₂ (for overall exercise capacity) and VE/VCO₂ slope (for ventilatory efficiency and prognosis) 1.

References

1
Guideline

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Dr.Oracle Medical Advisory Board & Editors, 2025

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Professional Medical Disclaimer

This information is intended for healthcare professionals. Any medical decision-making should rely on clinical judgment and independently verified information. The content provided herein does not replace professional discretion and should be considered supplementary to established clinical guidelines. Healthcare providers should verify all information against primary literature and current practice standards before application in patient care. Dr.Oracle assumes no liability for clinical decisions based on this content.

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