From the Research
For yeast infections under the breasts that haven't responded to nystatin, I recommend trying oral fluconazole 150mg taken once weekly for 2-3 weeks, as it has been shown to be the most effective treatment option in increasing mycological cure rates 1. This condition, called intertrigo, occurs because the warm, moist environment under breasts creates ideal conditions for yeast overgrowth. To manage the infection, keep the area clean and completely dry by washing with mild soap, thoroughly drying afterward, and using absorbent powders like Zeasorb or cornstarch (not talc). Some key points to consider:
- Wearing a supportive cotton bra and changing it daily helps reduce moisture.
- Consider placing a clean cotton cloth or specialized moisture-wicking fabric between the breasts and chest wall.
- For people with diabetes, maintaining good blood sugar control is essential as elevated glucose levels promote yeast growth.
- If these measures fail, see a healthcare provider as you may have a resistant fungal strain or a different condition altogether. It's also worth noting that while topical antifungal medications such as clotrimazole, miconazole, or ketoconazole cream can be effective, oral fluconazole has been shown to be more effective in increasing mycological cure rates, especially in cases where nystatin has failed 1.