What is the diagnosis for symptoms of fever, hemoptysis (coughing up blood), and cough?

Medical Advisory BoardAll articles are reviewed for accuracy by our Medical Advisory Board
Article Review Status
Submitted
Under Review
Approved

Last updated: April 5, 2025 • View editorial policy

Differential Diagnosis for Fever, Hemoptysis, and Cough

Single Most Likely Diagnosis

  • Pneumonia: This is the most likely diagnosis given the combination of fever, cough, and hemoptysis. Pneumonia is a common infection that can cause these symptoms, especially in the context of a bacterial or viral infection.

Other Likely Diagnoses

  • Tuberculosis (TB): TB is another likely diagnosis, particularly in areas where TB is prevalent. It can cause chronic cough, fever, and hemoptysis, especially in advanced cases.
  • Bronchitis: Acute or chronic bronchitis can cause cough and fever, and in some cases, hemoptysis, especially if there is an underlying condition like chronic obstructive pulmonary disease (COPD).
  • Pulmonary Embolism: While less common, pulmonary embolism can cause sudden onset of cough, fever, and hemoptysis, especially if there is an associated pulmonary infarction.

Do Not Miss Diagnoses

  • Lung Cancer: Although less likely, lung cancer is a critical diagnosis not to miss, as it can present with cough, fever, and hemoptysis, especially in smokers or those with a history of smoking.
  • Pulmonary Arteriovenous Malformation: This rare condition can cause hemoptysis due to abnormal connections between pulmonary arteries and veins, and it's crucial to diagnose to prevent severe bleeding.
  • Goodpasture Syndrome: An autoimmune disease that can cause pulmonary hemorrhage, leading to hemoptysis, and is often associated with renal failure.

Rare Diagnoses

  • Wegener's Granulomatosis (Granulomatosis with Polyangiitis): A rare autoimmune disorder that can cause inflammation of the blood vessels, leading to symptoms like cough, fever, and hemoptysis.
  • Pulmonary Vasculitis: Inflammation of the blood vessels in the lungs can cause a variety of symptoms, including cough, fever, and hemoptysis, and is often associated with systemic diseases.
  • Mitral Stenosis: A heart condition that can lead to pulmonary congestion and, in rare cases, hemoptysis, especially if there is associated pulmonary hypertension.

Professional Medical Disclaimer

This information is intended for healthcare professionals. Any medical decision-making should rely on clinical judgment and independently verified information. The content provided herein does not replace professional discretion and should be considered supplementary to established clinical guidelines. Healthcare providers should verify all information against primary literature and current practice standards before application in patient care. Dr.Oracle assumes no liability for clinical decisions based on this content.