Does low-level laser therapy (LLLT) or photobiomodulation (PBM) alleviate inflammation?

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Last updated: April 5, 2025View editorial policy

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From the Guidelines

Red light therapy is a promising treatment for reducing inflammation, with studies showing its efficacy in improving inflammatory acne. The use of red light therapy has been explored in various studies, including a 2002 study published in the British Journal of Dermatology 1, which found that a combination of red and blue light phototherapy was effective in improving both comedonal and inflammatory acne. This study suggests that red light therapy can help reduce inflammation by targeting the underlying causes of acne, including the reduction of sebum production and the size of sebaceous glands.

When considering the use of red light therapy for inflammation, it is essential to note that the treatment typically involves sessions lasting 10-20 minutes, performed 3-5 times weekly. The therapy works by decreasing inflammatory cytokines, reducing oxidative stress, and improving blood circulation to affected areas. Many users see results after 2-4 weeks of consistent use. Home devices are available, but proper eye protection should be worn during treatment.

While generally considered safe with minimal side effects, red light therapy should be approached cautiously by those with photosensitivity conditions or taking photosensitizing medications. The therapy can complement traditional anti-inflammatory treatments but shouldn't replace medical care for serious inflammatory conditions. It is crucial to consult with a healthcare professional before starting red light therapy, especially if you have any underlying medical conditions or concerns.

Key benefits of red light therapy for inflammation include:

  • Reduced inflammatory cytokines
  • Decreased oxidative stress
  • Improved blood circulation to affected areas
  • Minimal side effects
  • Can be used in conjunction with traditional anti-inflammatory treatments.

Overall, red light therapy is a viable option for reducing inflammation, particularly for inflammatory acne, and can be a useful adjunct to traditional treatments 1.

From the Research

Red Light Therapy and Inflammation

  • Red light therapy, also known as photobiomodulation (PBM) or low-level laser therapy, has been shown to reduce inflammation in various studies 2, 3.
  • The mechanism of PBM involves the absorption of red and near-infrared light by cells, which leads to increased ATP production, modulation of calcium levels, and activation of transcription factors, resulting in reduced inflammation 2.
  • PBM has been found to reduce markers of inflammation, such as reactive oxygen species and prostaglandins, in various animal models 2.
  • The therapy has been shown to be effective in reducing inflammation in various conditions, including joint disorders, traumatic injuries, lung disorders, and brain injuries 2, 3.

Comparison with Other Anti-Inflammatory Treatments

  • Omega-3 fatty acids, found in fish oil supplements, have also been shown to have anti-inflammatory effects, and may be a safer alternative to nonsteroidal anti-inflammatory drugs (NSAIDs) for treating nonsurgical neck or back pain 4.
  • NSAIDs, while effective in reducing pain and inflammation, have been associated with various organ damages, including gastrointestinal, cardiovascular, and renal complications 5.
  • Red light therapy, on the other hand, has been shown to be a safe and effective method for reducing inflammation, with minimal side effects 2, 3.

Professional Medical Disclaimer

This information is intended for healthcare professionals. Any medical decision-making should rely on clinical judgment and independently verified information. The content provided herein does not replace professional discretion and should be considered supplementary to established clinical guidelines. Healthcare providers should verify all information against primary literature and current practice standards before application in patient care. Dr.Oracle assumes no liability for clinical decisions based on this content.

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