What is the brand name of the topical gel containing clindamycin (CLINDAMYCIN) 1.2% and benzoyl peroxide (BENZOYL PEROXIDE) 2.5%?

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Brand Name of Clindamycin 1.2% and Benzoyl Peroxide 2.5%

The brand name for the topical gel containing clindamycin 1.2% and benzoyl peroxide 2.5% is BenzaClin. 1

Product Specifications

  • BenzaClin is a fixed-dose combination gel formulation specifically designed for twice-daily application in the treatment of acne vulgaris 1

  • The American Academy of Dermatology recommends applying a thin layer of BenzaClin to affected areas twice daily after thorough cleansing of the skin 1

Important Distinction from Other Formulations

  • Note that BenzaClin contains clindamycin 1% and benzoyl peroxide 5% in its standard formulation, not the 1.2%/2.5% concentration mentioned in your question 2, 3

  • The clindamycin 1.2%/benzoyl peroxide 2.5% concentration you're asking about does not appear to be a standalone marketed product based on the available evidence

  • A newer triple-combination product containing clindamycin phosphate 1.2%/adapalene 0.15%/benzoyl peroxide 3.1% gel (IDP-126) has been developed and approved, representing the first fixed-dose triple-combination for acne treatment 4, 5

Clinical Context

  • The combination of clindamycin and benzoyl peroxide in BenzaClin helps prevent bacterial resistance that may develop with clindamycin monotherapy 1

  • This combination is significantly more effective than either agent alone for treating inflammatory acne lesions 6, 3

  • BenzaClin is contraindicated in patients with hypersensitivity to clindamycin, benzoyl peroxide, or lincomycin 1, 6

References

Guideline

Recommended Dosage and Usage of BenzaClin

Praxis Medical Insights: Practical Summaries of Clinical Guidelines, 2025

Research

Clindamycin/benzoyl peroxide gel: a review of its use in the management of acne.

American journal of clinical dermatology, 2002

Guideline

Acne Treatment with Clindamycin and Benzoyl Peroxide

Praxis Medical Insights: Practical Summaries of Clinical Guidelines, 2025

Professional Medical Disclaimer

This information is intended for healthcare professionals. Any medical decision-making should rely on clinical judgment and independently verified information. The content provided herein does not replace professional discretion and should be considered supplementary to established clinical guidelines. Healthcare providers should verify all information against primary literature and current practice standards before application in patient care. Dr.Oracle assumes no liability for clinical decisions based on this content.

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