Code Blue: Immediate Management of Cardiac Arrest
Begin high-quality chest compressions immediately at 100-120 compressions per minute with a depth of at least 2 inches (5-6 cm) in adults, while simultaneously activating the emergency response system and retrieving an automated external defibrillator (AED). 1, 2
Immediate Recognition and Scene Safety
- Verify scene safety before approaching to avoid becoming a second victim 1
- Any collapsed, unresponsive person should be treated as cardiac arrest until proven otherwise—do not waste time trying to differentiate from seizures, syncope, or other conditions 3, 1
- Check responsiveness by shouting and tapping the victim 1
- Simultaneously assess breathing and pulse within 10 seconds maximum—look for absent or only gasping respirations while palpating for a pulse 1, 2
- If uncertain about pulse presence after 10 seconds, immediately start CPR rather than continuing to check 1
Critical Pitfall to Avoid
Agonal gasping occurs in over 50% of cardiac arrests and is commonly mistaken for normal breathing—any gasping or irregular breathing pattern in an unresponsive person indicates cardiac arrest 3, 1
High-Quality CPR Technique
Chest compressions are the single most critical intervention and must never be delayed or interrupted unnecessarily. 1, 2
Compression Parameters
- Rate: 100-120 compressions per minute (not faster, not slower) 1, 2
- Depth: At least 2 inches (5-6 cm) in adults—inadequate depth is a common fatal error 1, 2
- Allow complete chest recoil between compressions—leaning on the chest prevents cardiac refilling and dramatically reduces effectiveness 1, 2
- Minimize all interruptions—every pause in compressions decreases survival 1, 2
- Change compressors every 2 minutes (or sooner if fatigued) to maintain quality 2
Ventilation Strategy
- Use 30:2 compression-to-ventilation ratio (30 compressions, then 2 breaths) if no advanced airway is in place 1, 2
- Each breath should take 1 second and produce visible chest rise 3
- For untrained bystanders, compression-only CPR is acceptable and preferred over no CPR 3, 1
- Once an advanced airway is placed, provide continuous compressions without pauses and give 1 breath every 6 seconds (10 breaths/minute) asynchronously 2
Early Defibrillation
Time to defibrillation is the single greatest determinant of survival—survival decreases 10% per minute without defibrillation (or 3-4% per minute with CPR). 3
AED Application
- Apply the AED immediately when it arrives—do not delay CPR to retrieve it, but apply it the instant it becomes available 1, 2
- Pause compressions briefly (less than 10 seconds) to analyze rhythm 2
- For shockable rhythms (VF/pulseless VT): deliver one shock immediately (biphasic 120-200J or monophasic 360J) 2
- Resume CPR immediately after shock delivery without pausing to recheck pulse—continue for 2 minutes before next rhythm check 1, 2
- For non-shockable rhythms (PEA/asystole): continue CPR and reassess rhythm every 2 minutes 2
Medication Administration
Vascular Access
- Establish IV or intraosseous (IO) access while CPR is ongoing—do not interrupt compressions 2
Epinephrine Protocol
- Administer epinephrine 1 mg IV/IO every 3-5 minutes for all cardiac arrest rhythms (shockable and non-shockable) 2
Antiarrhythmic Therapy
- For persistent or recurrent VF/pulseless VT after initial shock: administer amiodarone 300 mg IV/IO or lidocaine 1-1.5 mg/kg IV/IO 2
Advanced Airway Management
- Consider endotracheal intubation or supraglottic airway placement, but never interrupt chest compressions for more than 10 seconds during placement attempts 2
- Confirm placement with continuous waveform capnography—this is mandatory, not optional 2
- Monitor capnography values: ETCO2 <10 mmHg indicates inadequate CPR quality and predicts poor outcomes 2
Reversible Causes: The H's and T's
Systematically consider and treat reversible causes while CPR continues: 2
The H's
- Hypovolemia: administer IV fluids
- Hypoxia: ensure adequate oxygenation and ventilation
- Hydrogen ion (acidosis): consider sodium bicarbonate if prolonged arrest
- Hypo/hyperkalemia: check point-of-care potassium, treat accordingly
- Hypothermia: rewarm if suspected
The T's
- Tension pneumothorax: needle decompression if suspected
- Tamponade (cardiac): bedside ultrasound, pericardiocentesis if confirmed
- Toxins: consider naloxone for suspected opioid overdose 1
- Thrombosis (pulmonary): consider thrombolytics if high suspicion
- Thrombosis (coronary): prepare for emergent cardiac catheterization
Special Population Considerations
Pediatric Modifications
- Compression-to-ventilation ratio: 30:2 for single rescuer, 15:2 for two or more rescuers 1
- Compression depth: at least one-third of anterior-posterior chest diameter 1
Pregnancy (≥20 weeks gestation)
- Provide manual left uterine displacement to relieve aortic compression 3
- Prepare for perimortem cesarean delivery if no ROSC within 4 minutes of resuscitation efforts 3
- Use 100% oxygen at ≥15 L/min—maternal oxygen reserves are critically reduced in pregnancy 3
Drowning Victims
- Modify the sequence to A-B-C (airway-breathing-compressions) rather than C-A-B because drowning is a hypoxic arrest 3
- Provide 5 cycles (approximately 2 minutes) of CPR before leaving to activate EMS if alone 3
- Do not attempt abdominal thrusts or Heimlich maneuver—water is rapidly absorbed and these maneuvers cause harm and delay 3
Hypothermia
- Continue resuscitation efforts until the patient is evaluated by advanced care providers—"no one is dead until they are warm and dead" 3
- Do not delay CPR to check temperature or wait for rewarming 3
Team Dynamics and Code Blue Activation
- Activate the code blue team immediately—use a single "bundled" emergency call (e.g., "Code Blue, Room 302") to alert all necessary responders simultaneously 3
- Assign specific roles: compressor, airway manager, medication administrator, recorder, team leader 2
- Use closed-loop communication to confirm all orders 2
- Consider assigning a "cognitive aid reader" to read resuscitation algorithms aloud—this has been shown to improve completion of critical steps during rare events 4
Monitoring Return of Spontaneous Circulation (ROSC)
- Check for ROSC every 2 minutes during rhythm checks 2
- Signs of ROSC: palpable pulse, sudden increase in ETCO2 (typically >40 mmHg), spontaneous arterial pressure waveform 2
- Once ROSC is achieved, initiate post-cardiac arrest care including targeted temperature management for patients who remain comatose 2
Critical Errors That Kill Patients
- Inadequate compression depth or rate—compressions must be hard and fast 1
- Excessive ventilation—hyperventilation decreases survival by increasing intrathoracic pressure and reducing venous return 3
- Prolonged pulse checks—if uncertain after 10 seconds, start CPR 1
- Leaning on the chest between compressions—prevents adequate cardiac refilling 1
- Excessive interruptions in compressions—every pause decreases coronary perfusion pressure and survival 1, 2
- Delayed defibrillation—survival decreases 10% per minute without shock delivery 3