From the FDA Drug Label
The FDA drug label does not answer the question.
From the Research
A patient with penile bleeding, UTI, and kidney stone should have their blood pressure monitored frequently, at least every 4 hours while awake, and more often if unstable. Initial monitoring should occur in a clinical setting with baseline measurements of both sitting and standing blood pressure to assess for orthostatic hypotension, which could indicate significant blood loss. For ongoing monitoring, the patient should check their BP at home 2-3 times daily using an automated cuff, recording readings in a log. If systolic BP drops below 90 mmHg or if the patient experiences dizziness, increased bleeding, or worsening pain, they should seek immediate medical attention. Blood pressure monitoring is crucial because hematuria can lead to hemodynamic instability, while pain from kidney stones can elevate BP. Additionally, certain antibiotics used for UTI treatment may affect blood pressure, as discussed in studies such as 1 which highlights the importance of considering antibiotic resistance patterns in UTI treatment. The patient should also monitor for fever, increasing pain, or changes in urine output, as these could indicate worsening infection or obstruction requiring prompt medical intervention. It is essential to prioritize the patient's morbidity, mortality, and quality of life when determining the monitoring plan, and to consider the potential impact of UTI treatment on blood pressure, as noted in studies such as 2 which evaluated the effectiveness of amoxicillin-clavulanate for UTIs caused by ceftriaxone non-susceptible Enterobacterales. Key considerations for the patient's monitoring plan include:
- Frequent blood pressure checks
- Monitoring for signs of worsening infection or obstruction
- Considering the potential impact of UTI treatment on blood pressure
- Prioritizing the patient's morbidity, mortality, and quality of life.