What are the odds of Anterior Cruciate Ligament (ACL) revision with Bone-Patellar Tendon-Bone (BPTB) graft and quadriceps tendon graft?

Medical Advisory BoardAll articles are reviewed for accuracy by our Medical Advisory Board
Educational purpose only • Exercise caution as content is pending human review
Article Review Status
Submitted
Under Review
Approved

Last updated: December 12, 2025View editorial policy

Personalize

Help us tailor your experience

Which best describes you? Your choice helps us use language that's most understandable for you.

ACL Revision Rates: BPTB vs Quadriceps Tendon Autografts

Based on the highest quality recent evidence, BPTB autograft demonstrates significantly lower revision rates (1.2% at 2 years) compared to quadriceps tendon autograft (3.6% at 2 years), representing a 60% lower risk of revision surgery. 1

Primary Evidence on Revision Risk

BPTB Autograft Performance

  • BPTB autograft has the lowest 2-year revision rate at 1.2% in a large registry study of 24,790 primary ACL reconstructions 1
  • When compared directly to quadriceps tendon, BPTB demonstrates a hazard ratio of 0.4 (95% CI 0.2-0.7, p<0.001), indicating 60% lower revision risk 1
  • This represents the most robust comparative data available from the Norwegian Knee Ligament Register spanning 2004-2021 1

Quadriceps Tendon Autograft Performance

  • Quadriceps tendon autograft shows a 2-year revision rate of 3.6%, which is the highest among the three major autograft types 1
  • Despite theoretical biomechanical advantages (70% greater ultimate load than patellar tendon, 20% more collagen fibrils per cross-sectional area), clinical revision rates remain elevated 2
  • The most common reasons for revision with quadriceps tendon are traumatic graft rupture and nontraumatic graft failure 1

Comparative Analysis with Hamstring Tendon

  • Hamstring tendon autograft demonstrates an intermediate 2-year revision rate of 2.5% 1
  • No statistically significant difference exists between quadriceps tendon and hamstring tendon revision risk (HR 1.1,95% CI 0.7-1.8) 1
  • In revision ACL reconstruction settings, hamstring grafts show a 19% failure rate compared to 10% for both quadriceps tendon and BPTB 3

Patient-Reported Outcomes

Functional Recovery

  • All three graft types (BPTB, quadriceps tendon, hamstring) demonstrate equivalent patient-reported outcomes at 2-year follow-up with no significant differences in KOOS Sport and Quality of Life subscores 1
  • Meta-analysis confirms no significant differences in IKDC subjective scores between quadriceps tendon and BPTB (p=0.39) or between quadriceps tendon and hamstring (p=0.25) 4
  • Side-to-side stability differences show no significant variation between graft types 4

Donor Site Morbidity Trade-offs

  • Quadriceps tendon demonstrates significantly lower donor site morbidity compared to BPTB (RR 0.17,95% CI 0.09-0.33, p<0.001) 4
  • Quadriceps tendon also shows lower donor site morbidity than hamstring tendon (RR 0.60,95% CI 0.39-0.93, p=0.02) 4
  • BPTB grafts are associated with increased anterior knee pain and kneeling pain compared to other autograft options 5

Clinical Decision Algorithm

When to Choose BPTB

  • Primary indication: Patients requiring the lowest possible revision risk, particularly young athletes in high-demand sports 1
  • Acceptable trade-off: Higher donor site morbidity and anterior knee pain for superior graft survival 5, 4
  • Contraindications: Patients with pre-existing patellofemoral pain or occupations requiring frequent kneeling 5

When to Consider Quadriceps Tendon

  • Patients where donor site morbidity is the primary concern over revision risk 4
  • Revision ACL reconstruction cases where BPTB or hamstring sites have been previously harvested 3
  • Patients requiring customizable graft dimensions (7-11mm diameter possible) 2
  • Critical caveat: Accept 3-fold higher revision risk compared to BPTB 1

Important Clinical Pitfalls

Patient Demographics Matter

  • Younger patients demonstrate higher revision rates across all graft types, with every 5-year increase in age reducing revision risk by 33% (HR 0.67,95% CI 0.61-0.73) 6
  • Male patients show 47% higher revision risk compared to females (HR 1.47,95% CI 1.04-2.07) 6
  • The quadriceps tendon cohort in registry data was younger (mean 23.5 years) and had more female patients (58.2%), potentially confounding direct comparisons 1

Rehabilitation Protocol Considerations

  • For BPTB grafts: Open kinetic chain exercises can begin at 4 weeks postoperatively in 90-45° ROM with added resistance 7, 5
  • For quadriceps tendon grafts: Similar rehabilitation timeline but requires specific donor site protection strategies 8
  • Closed kinetic chain exercises should be prioritized from week 2 for both graft types to minimize patellofemoral stress 7, 8

Long-term Osteoarthritis Risk

  • Graft source (patellar tendon vs other autografts) does not influence long-term osteoarthritis development (very low certainty evidence) 7, 9
  • Concomitant meniscectomy dramatically increases OA risk: partial meniscectomy OR 1.87 (95% CI 1.45-2.42), total medial meniscectomy OR 3.14 (95% CI 2.20-4.48) 7, 9
  • Cartilage injury at time of reconstruction increases OA odds 2.31-fold (95% CI 1.35-3.94) 7, 9

References

Research

Increased risk for early revision with quadriceps graft compared with patellar tendon graft in primary ACL reconstructions.

Knee surgery, sports traumatology, arthroscopy : official journal of the ESSKA, 2024

Research

Quadriceps Tendon Graft for Anterior Cruciate Ligament Reconstruction: THE GRAFT OF THE FUTURE!

Arthroscopy : the journal of arthroscopic & related surgery : official publication of the Arthroscopy Association of North America and the International Arthroscopy Association, 2019

Guideline

Risk of Patellar Tendon Tear Following Bone-Patellar Tendon-Bone ACL Reconstruction

Praxis Medical Insights: Practical Summaries of Clinical Guidelines, 2025

Guideline

Guideline Directed Topic Overview

Dr.Oracle Medical Advisory Board & Editors, 2025

Guideline

Rehabilitation Guidelines for Quadriceps Tendon Autograft in ACL Reconstruction

Praxis Medical Insights: Practical Summaries of Clinical Guidelines, 2025

Guideline

Arthrose-Entwicklung nach vorderer Kreuzbandruptur

Praxis Medical Insights: Practical Summaries of Clinical Guidelines, 2025

Professional Medical Disclaimer

This information is intended for healthcare professionals. Any medical decision-making should rely on clinical judgment and independently verified information. The content provided herein does not replace professional discretion and should be considered supplementary to established clinical guidelines. Healthcare providers should verify all information against primary literature and current practice standards before application in patient care. Dr.Oracle assumes no liability for clinical decisions based on this content.

Have a follow-up question?

Our Medical A.I. is used by practicing medical doctors at top research institutions around the world. Ask any follow up question and get world-class guideline-backed answers instantly.