Critical Warning: Hydrazine vs. Hydralazine Confusion
You are asking about HYDRAZINE, which is NOT a medication—it is an industrial chemical and known carcinogen with NO approved medical use. The evidence provided relates to HYDRALAZINE, a blood pressure medication with an entirely different chemical structure and purpose.
Hydrazine: Industrial Chemical, NOT a Drug
- Hydrazine is a toxic industrial chemical used in rocket fuel and chemical synthesis, NOT approved for any medical treatment 1
- The U.S. EPA, Department of Health and Human Services, and International Agency for Research on Cancer classify hydrazine as a possible human carcinogen 1
- Chronic exposure causes liver cancer in both rats and mice, along with kidney and nasal lesions 2
- Historical cancer studies showed hydrazine produced liver tumors even at maximum tolerable doses given lifelong 3
No Medical Dosing Exists
- There is NO safe or recommended medical dosage for hydrazine
- A 1979 cancer study attempted to use hydrazine sulfate (60 mg capsules 1-4 times daily) in terminal cancer patients, but found no tumor response and only brief subjective benefit in 3 of 25 patients 4
- Despite claims in the 1980s about anticachexia effects, hydrazine sulfate never gained FDA approval for any indication 5
Common Dangerous Mix-Up
If you meant to ask about HYDRALAZINE (the blood pressure medication):
- Hydralazine for heart failure: Start 37.5 mg three times daily, target 75 mg three times daily (combined with isosorbide dinitrate) 6, 7
- Hydralazine for acute hypertension: 10-20 mg IV or 25-50 mg oral 8, 6
- Maximum daily dose should remain under 300 mg 6
The FDA label 9 you referenced is for hydroxyzine (an antihistamine), NOT hydrazine or hydralazine—this represents a third distinct medication.