Differential Diagnosis of Small Bowel Obstruction at Age 60
In a 60-year-old patient with small bowel obstruction, adhesions from prior surgery remain the most common cause (55-75% of cases), but you must actively exclude hernias, malignancy, and inflammatory bowel disease—causes that collectively account for 35-45% of cases and require different management strategies. 1
Most Common Etiologies by Frequency
Adhesive Small Bowel Obstruction (55-75%)
- Prior abdominal surgery is the dominant risk factor, with 85% sensitivity and 78% specificity for predicting adhesive etiology 2
- Even remote surgical history (appendectomy decades prior) can cause adhesions 1
- However, do not assume adhesions without imaging confirmation—CT accuracy for identifying adhesive cause is only 52-76% 1
Hernias (10-15%)
- Examine all hernia orifices and previous surgical incision sites during physical examination 2
- Include groin hernias (inguinal, femoral), umbilical, and incisional hernias 1
- Internal hernias are increasingly recognized, particularly in patients with prior bariatric surgery 1
Malignancy (5-10%)
- Primary small bowel tumors or metastatic disease (carcinomatosis, peritoneal metastases) 1
- Document any unexplained weight loss or rectal bleeding in history 2
- Age 60 increases malignancy risk compared to younger patients 1
Inflammatory Bowel Disease (5%)
- Crohn's disease strictures are the primary IBD cause 1, 3
- Ask about chronic diarrhea, prior IBD diagnosis, or extraintestinal manifestations 1
Other Causes (10-15%)
- Gallstone ileus (particularly in elderly patients) 1
- Meckel's diverticulum complications 1
- Intussusception (rare in adults, often has lead point like tumor) 1
- Volvulus 1
- Radiation enteritis (if prior pelvic radiation) 1
- Endometriosis (less likely at age 60 but possible) 1
Critical Initial Assessment to Narrow Differential
History Elements That Guide Diagnosis
- Previous abdominal surgeries: Strongly suggests adhesions (85% sensitivity) 2
- Constipation pattern: Helps predict mechanical obstruction 2, 4
- Last bowel movement/gas passage: Complete vs. partial obstruction 2
- Medication review: Opioids, anticholinergics can cause pseudo-obstruction rather than true mechanical obstruction 1
- Weight loss/rectal bleeding: Raises concern for malignancy 2
Physical Examination Findings
- Abdominal distention has positive likelihood ratio of 16.8 for bowel obstruction 2
- Abnormal bowel sounds (hyperactive early, hypoactive late) predict obstruction 4
- Peritoneal signs indicate strangulation/ischemia requiring emergency surgery, though physical exam sensitivity for strangulation is only 48% 2
- Hernia examination may reveal external cause 2
- Digital rectal exam can detect masses or blood 2
Imaging Strategy to Establish Etiology
CT Abdomen/Pelvis with IV Contrast (First-Line)
- CT is the preferred imaging modality with >90% diagnostic accuracy for identifying obstruction and predicting need for surgery 1, 2
- No oral contrast needed for high-grade obstruction—non-opacified fluid provides adequate contrast 2
- CT helps differentiate causes by excluding hernias, masses, inflammatory changes 1
- CT accuracy for specific adhesive diagnosis is limited (52-76%), so adhesions remain a diagnosis of exclusion 1
Signs on CT Suggesting Specific Etiologies
- Closed loop, mesenteric edema, abnormal bowel wall enhancement: Suggests strangulation/ischemia requiring immediate surgery 1, 2
- Transition point with mass: Malignancy 2
- Transition point at hernia orifice: Hernia 1
- Bowel wall thickening with inflammatory changes: IBD or ischemia 2
Alternative Imaging When CT Unavailable
- Ultrasound has 90% sensitivity and 96% specificity, particularly useful if radiation exposure is a concern 2, 4
- Plain radiography has limited value (50-60% sensitivity) and should not delay CT 2
Key Pitfalls to Avoid
Don't Assume Adhesions Without Excluding Other Causes
- Even with prior surgery history, 25-45% of SBO cases have non-adhesive causes 1
- CT is essential to exclude hernias and malignancy 1
Don't Miss Pseudo-Obstruction
- Review medications carefully—opioids and anticholinergics cause narcotic bowel syndrome mimicking mechanical obstruction 1
- Consider metabolic causes (hypokalemia, hypothyroidism) 1, 2
Don't Delay Surgery for Ischemia
- Mortality increases from 10% to 25-30% with bowel necrosis/perforation 2, 3
- Signs requiring immediate surgery: peritonitis, CT findings of ischemia (pneumatosis, portal venous gas, lack of enhancement) 1, 2
Don't Overlook Malignancy in "Virgin Abdomen"
- In patients without prior surgery, malignancy and hernias become leading causes 1
- Age 60 warrants heightened suspicion for cancer 1
Laboratory Tests to Support Differential
- Marked leukocytosis (>10,000/mm³) suggests peritonitis or ischemia 2, 3
- Elevated lactate indicates possible bowel ischemia 2, 3
- CRP >75 may indicate peritonitis 2
- Electrolyte abnormalities (hypokalemia) need correction and may contribute to ileus 2
- Screen for hypothyroidism, which can cause pseudo-obstruction 1