What is the ICD-10 (International Classification of Diseases, 10th Revision) code for a sperm count check and urology evaluation?

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ICD-10 Codes for Sperm Count Check and Urology Evaluation

For a sperm count check and urology evaluation, use ICD-10 code N46.9 (Male infertility, unspecified) or Z31.41 (Encounter for fertility testing) as the primary diagnostic code, depending on whether infertility is suspected or this is purely screening.

Primary ICD-10 Codes for Sperm Count Testing

N46.9 - Male infertility, unspecified is the most appropriate code when:

  • The patient has concerns about fertility potential 1
  • The couple has not achieved conception after one year of unprotected intercourse 1
  • Male infertility risk factors exist (history of cryptorchidism, varicocele, etc.) 1

Z31.41 - Encounter for fertility testing should be used when:

  • The patient requests fertility evaluation without a current partner 1
  • This is a screening evaluation before attempting conception 2
  • No specific infertility diagnosis has been established 2

Additional Specific ICD-10 Codes Based on Clinical Findings

If the initial evaluation reveals specific abnormalities, use more precise codes:

For oligospermia (low sperm count):

  • N46.11 - Organic oligospermia 3
  • N46.121 - Oligospermia due to drug therapy 4
  • N46.129 - Oligospermia due to other extratesticular causes 4

For azoospermia (absent sperm):

  • N46.01 - Organic azoospermia 4
  • N46.021 - Azoospermia due to drug therapy 4
  • N46.029 - Azoospermia due to other extratesticular causes 4

For hormonal abnormalities identified during workup:

  • E29.1 - Testicular hypofunction (if low testosterone with elevated FSH/LH) 4
  • E23.0 - Hypopituitarism (if low testosterone with low/normal FSH/LH) 4

Essential Components of the Urological Evaluation

The comprehensive evaluation should include 1:

Reproductive history assessment:

  • Frequency and timing of intercourse 1
  • Duration of current infertility 1
  • Prior fertility history 1
  • Sexual history including sexually transmitted diseases 1
  • Gonadal toxin exposure including heat 1

Physical examination findings that determine coding:

  • Testicular volume measurement (normal >15 mL; small testis suggests N46.01) 1
  • Presence of varicocele (use I86.1 as secondary code) 1
  • Congenital bilateral absence of vas deferens (use Q55.4) 1
  • Cryptorchidism history (use Z87.710 for personal history) 1

Laboratory testing requirements:

  • At least two semen analyses performed one month apart 1, 2
  • Serum testosterone and FSH if sperm concentration <10 million/mL 2
  • Genetic testing (karyotype, Y-chromosome microdeletions) for severe oligospermia (<5 million/mL) or azoospermia 1, 4, 2

Common Pitfalls in ICD-10 Coding for Male Infertility

Avoid using N46.9 when more specific codes apply: If semen analysis reveals oligospermia or azoospermia, use the specific subcategory codes (N46.11 or N46.01) rather than the unspecified code 4.

Document secondary diagnoses that affect fertility: Conditions like varicocele (I86.1), hypogonadism (E29.1), or history of cryptorchidism (Z87.710) should be coded separately as they impact treatment decisions and prognosis 1, 4.

Use Z31.41 appropriately for screening: This code is specifically for fertility testing encounters and should not be used if infertility has already been diagnosed 2.

Consider metabolic comorbidities: Men with low sperm counts have 12-fold increased risk of hypogonadism and higher prevalence of metabolic syndrome, so additional codes for obesity (E66.-), hypertension (I10), or dyslipidemia (E78.-) may be warranted 3.

Coding for Follow-Up Evaluations

For repeat semen analysis: Continue using the same primary code (N46.9, N46.11, or N46.01) with modifier indicating this is a subsequent encounter 1, 2.

For advanced testing: If sperm DNA fragmentation or oxidative stress testing is performed, maintain the primary infertility code while documenting the specific indication 5.

For genetic testing encounters: Use Z31.430 (Encounter for genetic testing of male for procreative management) as a secondary code when performing karyotype or Y-chromosome microdeletion analysis 1, 4, 2.

References

Guideline

Guideline Directed Topic Overview

Dr.Oracle Medical Advisory Board & Editors, 2025

Guideline

Initial Evaluation for Infertility

Praxis Medical Insights: Practical Summaries of Clinical Guidelines, 2025

Guideline

Non-Obstructive Azoospermia Causes and Diagnosis

Praxis Medical Insights: Practical Summaries of Clinical Guidelines, 2025

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Professional Medical Disclaimer

This information is intended for healthcare professionals. Any medical decision-making should rely on clinical judgment and independently verified information. The content provided herein does not replace professional discretion and should be considered supplementary to established clinical guidelines. Healthcare providers should verify all information against primary literature and current practice standards before application in patient care. Dr.Oracle assumes no liability for clinical decisions based on this content.

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