What is the recommended imaging for suspected Epidural Hematoma (EDH)?

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Last updated: December 13, 2025View editorial policy

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Imaging for Suspected Epidural Hematoma (EDH)

Non-contrast CT of the head is the gold standard and mandatory first-line imaging for suspected epidural hematoma, providing rapid, accurate diagnosis that directly guides surgical decision-making. 1

Primary Imaging Recommendation

CT head without IV contrast is the definitive initial study for suspected EDH and should be performed immediately 1:

  • Rated 9/9 ("usually appropriate") by the American College of Radiology for suspected parenchymal hemorrhage including EDH 1
  • Provides rapid acquisition critical in trauma settings where time to diagnosis directly impacts mortality 1
  • Demonstrates the characteristic lenticular or biconvex high-density collection between skull and dura 1
  • Identifies associated skull fractures, which are present in the majority of EDH cases and predict arterial bleeding sources 1, 2
  • Allows immediate assessment of mass effect, midline shift, and need for emergent surgical evacuation 2

When to Add Vascular Imaging

CT angiography (CTA) head with IV contrast should be obtained concurrently when 1:

  • Skull fracture crosses a dural venous sinus or involves the jugular bulb/foramen (41% risk of venous sinus thrombosis) 1
  • Active contrast extravasation ("spot sign") is suspected, which predicts EDH expansion and need for surgery 2
  • The study can be performed immediately after non-contrast CT while the patient remains on the table 1

Follow-Up Imaging Protocol

Repeat non-contrast CT head at 6-13 hours after initial scan is critical for 2:

  • Patients managed non-operatively with initial small EDH
  • Those with concurrent subarachnoid hemorrhage (SAH), which is the strongest predictor of EDH enlargement (OR 2.60) 2
  • This timing window captures nearly all cases of EDH expansion that may require delayed surgery 2

Immediate post-operative CT should be standard practice following EDH evacuation when 3:

  • Any contralateral skull fracture is present
  • There is suspicion of bilateral bleeding
  • Asynchronous contralateral EDH, though rare, can develop and requires immediate detection 3

Role of MRI

MRI is NOT indicated for acute suspected intracranial EDH 1:

  • CT remains superior for acute hemorrhage detection and surgical planning 1
  • MRI is too slow in the acute trauma setting where rapid diagnosis is essential 1
  • MRI head without IV contrast is rated only 8/9 (versus CT's 9/9) for parenchymal hemorrhage 1

MRI has a specific role only for spinal EDH when 4, 5:

  • Acute cauda equina syndrome or progressive myelopathy is present
  • T2-weighted sequences show characteristic heterogeneous hyperintensity with focal hypointensity 4
  • However, severity of neurologic deficit—not imaging findings—drives management decisions 4

Critical Imaging Predictors of Poor Outcome

The following CT findings mandate immediate neurosurgical consultation 2:

  • Large initial EDH size (>20 mL volume threshold historically associated with worse outcomes) 6
  • Arterial bleeding source identified by skull fracture location crossing meningeal artery grooves 2
  • Mixed attenuation or "spot sign" indicating active hemorrhage 2
  • Midline shift of any degree 2
  • EDH enlargement on follow-up imaging, which is the only predictor of need for delayed surgery 2

Common Pitfalls to Avoid

  • Never obtain MRI as initial imaging in acute head trauma with suspected EDH—this delays life-saving diagnosis 1
  • Do not skip follow-up CT at 6-13 hours in non-operative cases, especially with concurrent SAH 2
  • Do not assume small EDH is safe—28% enlarge on follow-up, and expansion predicts need for surgery 2
  • Always obtain immediate post-operative CT when contralateral fracture is present to detect asynchronous bilateral EDH 3
  • Do not use contrast-enhanced CT initially—it adds no value and delays diagnosis; non-contrast CT is sufficient and faster 1

References

Guideline

Guideline Directed Topic Overview

Dr.Oracle Medical Advisory Board & Editors, 2025

Research

Risk Factors for Epidural Hematoma Expansion and the Need for Surgery.

AJNR. American journal of neuroradiology, 2025

Research

Acute spontaneous spinal epidural hematomas.

AJNR. American journal of neuroradiology, 1999

Professional Medical Disclaimer

This information is intended for healthcare professionals. Any medical decision-making should rely on clinical judgment and independently verified information. The content provided herein does not replace professional discretion and should be considered supplementary to established clinical guidelines. Healthcare providers should verify all information against primary literature and current practice standards before application in patient care. Dr.Oracle assumes no liability for clinical decisions based on this content.

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