What is the recommended dose of paracetamol (acetaminophen) syrup for an 11kg pediatric patient?

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Paracetamol Syrup Dosing for an 11kg Pediatric Patient

For an 11kg child, administer 110-165 mg of paracetamol (acetaminophen) per dose, given every 4-6 hours, not exceeding 5 doses in 24 hours or a maximum daily dose of 660 mg. 1

Weight-Based Dosing Calculation

  • The standard dose of acetaminophen is 10-15 mg/kg per dose, given every 4-6 hours 1
  • For an 11kg child:
    • Minimum dose: 110 mg (10 mg/kg × 11 kg)
    • Maximum dose: 165 mg (15 mg/kg × 11 kg)
  • The maximum daily dose should never exceed 60 mg/kg per day (660 mg for an 11kg child) or 5 doses in 24 hours 1

Practical Syrup Administration

  • Oral syrup formulation is absorbed more rapidly and provides a more consistent response compared to suppositories 1
  • Most pediatric paracetamol syrups are available in concentrations of 160 mg/5 mL (32 mg/mL) 2
  • For a standard 160 mg/5 mL concentration:
    • 3.4-5.2 mL per dose delivers 110-165 mg
    • Practical dosing: 3.5-5 mL every 4-6 hours 2

Dosing Interval and Frequency

  • Administer every 4-6 hours as needed for fever or pain 1
  • Do not exceed 5 doses in a 24-hour period 1, 2
  • Maintain at least 4 hours between doses 1

Important Safety Considerations

  • Never exceed 60 mg/kg per day to prevent hepatotoxicity 1
  • Single ingestions of more than ten times the recommended dose (>150 mg/kg) are potentially toxic 3
  • Chronic overdosing (>140 mg/kg/day for several days) carries risk of serious liver toxicity 3
  • For children under 2 years of age, FDA labeling recommends consulting a doctor, though clinical guidelines support weight-based dosing 2

Clinical Context

  • Paracetamol is the first-line choice for treatment of both fever and pain in children 3
  • It is remarkably well tolerated when used in recommended doses with few side effects 3
  • The 10-15 mg/kg dosing range has been validated through extensive clinical and pharmacokinetic data 4

References

Guideline

Pediatric Acetaminophen and Ibuprofen Dosing Guidelines

Praxis Medical Insights: Practical Summaries of Clinical Guidelines, 2025

Research

Paracetamol efficacy and safety in children: the first 40 years.

American journal of therapeutics, 2000

Research

Pediatric dosing of acetaminophen.

Pediatric pharmacology (New York, N.Y.), 1983

Professional Medical Disclaimer

This information is intended for healthcare professionals. Any medical decision-making should rely on clinical judgment and independently verified information. The content provided herein does not replace professional discretion and should be considered supplementary to established clinical guidelines. Healthcare providers should verify all information against primary literature and current practice standards before application in patient care. Dr.Oracle assumes no liability for clinical decisions based on this content.

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