Albumin-to-Creatinine Ratio Calculation
With albumin 4.4 mg/dL and creatinine 0.68 g/dL, the albumin-to-creatinine ratio is 6.5 mg/g, which falls in the normal range (A1 category: <30 mg/g). 1
Calculation Method
The albumin-to-creatinine ratio is calculated by dividing the urine albumin concentration (in mg/dL) by the urine creatinine concentration (in g/dL):
- Formula: (Albumin in mg/dL) ÷ (Creatinine in g/dL) = ACR in mg/g 1, 2
- Your values: 4.4 mg/dL ÷ 0.68 g/dL = 6.47 mg/g (approximately 6.5 mg/g)
Clinical Interpretation
This result indicates normal kidney function with no evidence of albuminuria. 1
Albuminuria Categories (KDIGO/ADA Classification)
- A1 (Normal to Mildly Increased): <30 mg/g - Your result falls here 1
- A2 (Moderately Increased): 30-299 mg/g 1
- A3 (Severely Increased): ≥300 mg/g 1
Clinical Significance
- Cardiovascular and kidney disease risk begins at values consistently above 30 mg/g, so your result of 6.5 mg/g indicates very low risk 1
- This ratio is a continuous marker for cardiovascular event risk at all levels of kidney function, with risk stratification becoming clinically relevant above the 30 mg/g threshold 1
- Normal reference range is ≤30 mg albumin/g creatinine according to standardized laboratory reporting 1, 2
Important Caveats
- First-morning spot urine collections are preferred for children and adolescents to avoid confounding from orthostatic proteinuria 1, 2
- Patients should refrain from vigorous exercise for 24 hours before sample collection, as exercise can transiently increase albumin excretion 1, 2
- A single elevated value (>30 mg/g) should be confirmed on 2 of 3 samples collected within 3-6 months before diagnosing persistent albuminuria 1