What is the best management for subconjunctival hemorrhage?

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Management of Subconjunctival Hemorrhage

Subconjunctival hemorrhage requires observation and supportive care only, with no specific medical intervention needed in the vast majority of cases. 1

Initial Management

The primary approach is reassurance and observation, as subconjunctival hemorrhage is a benign, self-limiting condition. 1 The American Academy of Ophthalmology classifies this as a common postoperative concern best treated with observation or a short course of supportive therapy. 1

Supportive Measures

  • Apply cold compresses in the first 24-48 hours to reduce bleeding extension (general ophthalmology practice)
  • Use artificial tears for comfort if irritation is present 1
  • Avoid aspirin and NSAIDs during the acute phase unless medically necessary 2

The hemorrhage typically resolves spontaneously within 1-2 weeks without intervention, as the blood is reabsorbed naturally. 1

When to Investigate Further

Most cases require no workup, but specific circumstances warrant additional evaluation: 2

Red Flags Requiring Investigation

  • Recurrent episodes without identifiable cause - Consider systemic hypertension screening, bleeding disorder workup, and medication review 2, 3
  • Bilateral or severe hemorrhages - Evaluate for blood dyscrasias, coagulation disorders, or increased intrathoracic pressure from vomiting/coughing 3
  • Patients on anticoagulation therapy - Check PT/INR levels if on warfarin, as prolonged prothrombin time can cause severe hemorrhages 3
  • Associated with trauma or contact lens use in younger patients 2
  • Elderly patients with vascular risk factors - Screen for hypertension, diabetes, and arteriosclerosis 2

Important caveat: Routine hemostatic screening (bleeding time, PFA-100, platelet aggregometry, von Willebrand testing) is not indicated for isolated subconjunctival hemorrhage, as the prevalence of hemostatic abnormalities is no different from the general population. 4 These tests should only be ordered if there are other bleeding manifestations or strong clinical suspicion. 4

Prevention Strategies

For patients undergoing procedures that may cause subconjunctival hemorrhage (such as intravitreal injections):

  • Topical oxymetazoline 30 minutes before the procedure reduces hemorrhage incidence from 72% to 51% 5
  • This is a single, cost-effective intervention that improves patient satisfaction and compliance with ongoing treatment 5

Follow-up

No routine follow-up is necessary for uncomplicated cases. 1 Patients should be instructed to return only if:

  • The hemorrhage does not resolve within 2-3 weeks
  • Vision changes occur
  • Pain develops (subconjunctival hemorrhage itself is painless)
  • Recurrent episodes occur 2

References

Guideline

Guideline Directed Topic Overview

Dr.Oracle Medical Advisory Board & Editors, 2025

Research

Subconjunctival hemorrhage: risk factors and potential indicators.

Clinical ophthalmology (Auckland, N.Z.), 2013

Research

Subconjunctival and external hemorrhage secondary to oral anticoagulation.

Journal of the American Optometric Association, 1990

Research

Oxymetazoline: reduction of subconjunctival hemorrhage incidence after intravitreal injections.

Canadian journal of ophthalmology. Journal canadien d'ophtalmologie, 2019

Professional Medical Disclaimer

This information is intended for healthcare professionals. Any medical decision-making should rely on clinical judgment and independently verified information. The content provided herein does not replace professional discretion and should be considered supplementary to established clinical guidelines. Healthcare providers should verify all information against primary literature and current practice standards before application in patient care. Dr.Oracle assumes no liability for clinical decisions based on this content.

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