What is the diagnosis for a 36-year-old woman, gravida (number of times pregnant) 3, para (number of viable births) 2, at 35 weeks gestation, presenting with rupture of membranes, painless vaginal bleeding, and undetectable fetal heart tones, with a history of hypertension and two previous term cesarean deliveries?

Medical Advisory BoardAll articles are reviewed for accuracy by our Medical Advisory Board
Educational purpose only • Exercise caution as content is pending human review
Article Review Status
Submitted
Under Review
Approved

Last updated: April 7, 2025View editorial policy

Personalize

Help us tailor your experience

Which best describes you? Your choice helps us use language that's most understandable for you.

Differential Diagnosis

  • Single most likely diagnosis
    • Placental abruption: This condition is characterized by the separation of the placenta from the uterus, which can cause painless vaginal bleeding, rupture of membranes, and fetal distress. The patient's history of hypertension and lack of prenatal care increase her risk for this condition. The presence of bloody fluid after the rupture of membranes and the inability to detect fetal heart tones on Doppler ultrasound support this diagnosis.
  • Other Likely diagnoses
    • Uterine rupture: Given the patient's history of two previous cesarean deliveries, uterine rupture is a possible diagnosis, especially if the patient had a classical incision or a previous uterine rupture. However, the patient's symptoms and the nontender uterus make this diagnosis less likely.
    • Placenta previa: This condition, where the placenta covers the cervical os, can cause painless vaginal bleeding. However, the patient's symptoms of rupture of membranes and the presence of bloody fluid make placental abruption more likely.
  • Do Not Miss (ddxs that may not be likely, but would be deadly if missed.)
    • Uterine dehiscence: Similar to uterine rupture, uterine dehiscence is a possible diagnosis given the patient's history of previous cesarean deliveries. Although less likely, it is crucial to consider this diagnosis due to its potential severity.
    • Amniotic fluid embolism: Although rare, amniotic fluid embolism is a life-threatening condition that can occur after rupture of membranes. The patient's symptoms of rupture of membranes and the presence of bloody fluid make this diagnosis possible, albeit unlikely.
  • Rare diagnoses
    • Vasa previa: This condition, where fetal blood vessels are present in the membranes covering the cervical os, can cause vaginal bleeding and fetal distress after rupture of membranes. However, this diagnosis is rare and less likely given the patient's symptoms and history.
    • Fetal demise: Although the inability to detect fetal heart tones on Doppler ultrasound raises concerns about fetal well-being, fetal demise is a rare diagnosis in this scenario, especially given the patient's report of normal fetal movement earlier in the day.

Professional Medical Disclaimer

This information is intended for healthcare professionals. Any medical decision-making should rely on clinical judgment and independently verified information. The content provided herein does not replace professional discretion and should be considered supplementary to established clinical guidelines. Healthcare providers should verify all information against primary literature and current practice standards before application in patient care. Dr.Oracle assumes no liability for clinical decisions based on this content.

Have a follow-up question?

Our Medical A.I. is used by practicing medical doctors at top research institutions around the world. Ask any follow up question and get world-class guideline-backed answers instantly.