What is the difference in fatty acid composition between farmed salmon and wild-caught (wild) salmon?

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From the Guidelines

Farmed salmon and wild salmon have distinct differences in their fat composition, with farmed salmon containing higher levels of total fat and a less favorable omega-3 to omega-6 ratio compared to wild salmon. The fat content in farmed salmon is roughly twice that of wild salmon, with levels around 12-16% compared to 6-8% in wild varieties 1. While both types provide beneficial omega-3 fatty acids, farmed salmon generally has higher levels of omega-6 fatty acids due to grain-based feed, resulting in a less optimal omega-3:omega-6 ratio than wild salmon. Some key points to consider about the fat composition of farmed and wild salmon include:

  • Farmed salmon has similar or higher levels of omega-3 fatty acids compared to wild salmon, but the omega-3:omega-6 ratio is less favorable 1
  • Wild salmon derives its omega-3s from consuming marine organisms in its natural diet, while farmed salmon's fatty acid profile directly reflects its manufactured feed
  • The higher fat content in farmed salmon also means it may contain more fat-soluble contaminants like PCBs and dioxins, though levels are regulated and generally considered safe for consumption 1
  • Despite these differences, both types of salmon remain nutritious protein sources rich in essential nutrients, and women who are or may become pregnant or nursing can consume 2-3 servings/week of a variety of fish lower in mercury, including salmon, while following FDA guidance 1

From the Research

Fat Composition of Farmed and Wild Salmon

  • The fat composition of farmed and wild salmon differs significantly, with farmed salmon having greater levels of total lipid (average 16.6%) compared to wild salmon (average 6.4%) 2.
  • The n-3 to n-6 ratio is also different, with wild salmon having a ratio of about 10 and farmed salmon having a ratio of 3-4 2.
  • Farmed salmon have higher levels of omega-3 fatty acids, but also higher levels of contaminants such as polychlorinated biphenyls (PCBs), dioxins, and chlorinated pesticides 2.

Health Benefits of Omega-3 Fatty Acids

  • Omega-3 fatty acids, particularly EPA and DHA, have been linked to various health benefits, including fetal development, cardiovascular function, and cognitive function 3, 4, 5, 6.
  • However, the evidence for the cardiovascular benefits of omega-3 fatty acids is mixed, with some studies suggesting little or no effect on mortality or cardiovascular events 5, 6.
  • Increasing intake of omega-3 fatty acids may slightly reduce the risk of coronary heart disease mortality and events, as well as reduce serum triglycerides 6.

Comparison of Farmed and Wild Salmon

  • While both farmed and wild salmon are good sources of omega-3 fatty acids, the higher levels of contaminants in farmed salmon may reduce the net health benefits of consumption 2.
  • Wild salmon generally has a more favorable n-3 to n-6 ratio and lower levels of contaminants, making it a potentially healthier choice 2.

References

Guideline

Guideline Directed Topic Overview

Dr.Oracle Medical Advisory Board & Editors, 2025

Research

Lipid composition and contaminants in farmed and wild salmon.

Environmental science & technology, 2005

Research

Omega-3 fatty acids EPA and DHA: health benefits throughout life.

Advances in nutrition (Bethesda, Md.), 2012

Research

Omega-3 fatty acids, cardiovascular risk, and the resolution of inflammation.

FASEB journal : official publication of the Federation of American Societies for Experimental Biology, 2019

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Professional Medical Disclaimer

This information is intended for healthcare professionals. Any medical decision-making should rely on clinical judgment and independently verified information. The content provided herein does not replace professional discretion and should be considered supplementary to established clinical guidelines. Healthcare providers should verify all information against primary literature and current practice standards before application in patient care. Dr.Oracle assumes no liability for clinical decisions based on this content.

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