What is the diagnosis for a 37-year-old woman presenting with diffuse abdominal pain, nausea, vomiting, and fever, one week post-laparoscopic hysterectomy (surgical removal of the uterus) for severe endometriosis, with laboratory results showing leukocytosis (elevated white blood cell count) and normal urinalysis?

Medical Advisory BoardAll articles are reviewed for accuracy by our Medical Advisory Board
Educational purpose only • Exercise caution as content is pending human review
Article Review Status
Submitted
Under Review
Approved

Last updated: April 7, 2025View editorial policy

Personalize

Help us tailor your experience

Which best describes you? Your choice helps us use language that's most understandable for you.

Differential Diagnosis for Post-Laparoscopic Hysterectomy Patient

The patient presents with abdominal pain, nausea, vomiting, and increased vaginal discharge after a laparoscopic hysterectomy. The following differential diagnoses are considered:

  • Single Most Likely Diagnosis

    • Postoperative ileus: This condition is characterized by a temporary cessation of the normal contractions of the bowel muscles, leading to abdominal distension, nausea, vomiting, and bloating. The patient's symptoms of diffuse abdominal pain, bloating, nausea, and vomiting, along with the absence of severe tenderness or guarding, support this diagnosis. The fact that she is passing flatus suggests that the ileus is partial and may resolve with supportive care.
  • Other Likely Diagnoses

    • Infection of the vaginal cuff or pelvic cavity: The presence of fever (38 C), increased vaginal discharge, and a recent surgical history raises the possibility of an infection. However, the lack of significant pelvic tenderness or purulent discharge makes this less likely.
    • Constipation: Although the patient is passing flatus, constipation could contribute to her symptoms of abdominal distension and discomfort. The recent surgery and possible use of opioid analgesics could predispose her to constipation.
    • Adhesions or internal hernia: These complications can occur after laparoscopic surgery, leading to bowel obstruction. However, the patient's ability to pass flatus and the absence of severe abdominal pain or tenderness make this less likely at present.
  • Do Not Miss Diagnoses

    • Bowel injury or perforation: Although rare, bowel injury during laparoscopic hysterectomy can lead to peritonitis, sepsis, and severe consequences if not promptly recognized and treated. The presence of fever, abdominal pain, and vomiting necessitates careful consideration of this possibility, despite the lack of clear signs of peritonitis.
    • Hemorrhage or hematoma: Postoperative bleeding can occur internally or externally and may lead to hypovolemic shock. The patient's stable vital signs and lack of significant abdominal tenderness make this less likely, but it remains a critical diagnosis not to miss.
    • Ureteral injury: Injury to the ureters during hysterectomy can lead to severe consequences, including sepsis and renal damage. The patient's normal urinalysis and absence of flank pain or costovertebral angle tenderness decrease the likelihood, but this diagnosis should be considered, especially if the patient's condition worsens.
  • Rare Diagnoses

    • Deep vein thrombosis (DVT) or pulmonary embolism (PE): Although less common in this clinical context, DVT or PE can occur postoperatively, especially in patients with risk factors such as immobility or history of thromboembolic events. The patient's current symptoms do not strongly suggest these conditions, but they should be considered if there are unexplained signs of respiratory distress or leg swelling.
    • Vaginal cuff dehiscence: This is a rare but serious complication where the vaginal cuff opens, potentially leading to evisceration of bowel contents into the vagina. The presence of watery vaginal discharge and the fact that the vaginal cuff appears closed on examination make this less likely, but it should be considered if the patient's condition deteriorates or if there are signs of peritonitis.

Professional Medical Disclaimer

This information is intended for healthcare professionals. Any medical decision-making should rely on clinical judgment and independently verified information. The content provided herein does not replace professional discretion and should be considered supplementary to established clinical guidelines. Healthcare providers should verify all information against primary literature and current practice standards before application in patient care. Dr.Oracle assumes no liability for clinical decisions based on this content.

Have a follow-up question?

Our Medical A.I. is used by practicing medical doctors at top research institutions around the world. Ask any follow up question and get world-class guideline-backed answers instantly.