Is pneumobilia (air in the bile ducts) common after cholecystectomy (gallbladder removal)?

Medical Advisory BoardAll articles are reviewed for accuracy by our Medical Advisory Board
Educational purpose only • Exercise caution as content is pending human review
Article Review Status
Submitted
Under Review
Approved

Last updated: December 15, 2025View editorial policy

Personalize

Help us tailor your experience

Which best describes you? Your choice helps us use language that's most understandable for you.

Pneumobilia After Cholecystectomy

Pneumobilia is NOT a common finding after routine cholecystectomy and should prompt investigation for complications when present. The available guidelines on cholecystectomy complications do not list pneumobilia as an expected post-operative finding 1, 2, 3.

Why Pneumobilia is Uncommon After Standard Cholecystectomy

  • Standard cholecystectomy does not create a biliary-enteric connection, which is the primary mechanism for pneumobilia 4.
  • The gallbladder is removed and the cystic duct is ligated, leaving the biliary system closed without communication to the gastrointestinal tract 1.
  • Pneumobilia occurs when there is an abnormal connection between the biliary tract and the gastrointestinal tract, which is not created during routine cholecystectomy 4, 5.

When Pneumobilia DOES Occur Post-Operatively

Pneumobilia is expected only in specific surgical scenarios:

  • After biliary-enteric anastomosis procedures such as choledochojejunostomy or hepaticojejunostomy 4.
  • Following endoscopic sphincterotomy (ERCP with papillosphincterotomy), which creates incompetence of the sphincter of Oddi 4, 5.
  • After Whipple procedure or other surgically created biliary-enteric connections 4.

Clinical Significance When Found After Cholecystectomy

If pneumobilia is discovered after routine cholecystectomy, investigate for serious complications:

  • Bile duct injury with fistula formation to the duodenum or other bowel segments 4, 5.
  • Cholecystoduodenal fistula (if the gallbladder was not completely removed or if injury occurred) 4.
  • Gas-forming infection such as emphysematous cholecystitis or cholangitis 6, 7.
  • Instrumentation-related if the patient underwent intraoperative cholangiography or post-operative ERCP 4.

Common Pitfall to Avoid

  • Do not dismiss pneumobilia as a benign incidental finding in post-cholecystectomy patients without prior biliary-enteric anastomosis 7.
  • Persistent pneumobilia can lead to ascending cholangitis and bacteremia, even when initially asymptomatic 7.
  • Evaluate for bile duct injury, which occurs in 0.4-1.5% of laparoscopic cholecystectomies and can present with delayed symptoms 1, 3.

Recommended Workup

When pneumobilia is identified after cholecystectomy:

  • Assess liver function tests to evaluate for bile duct injury 2.
  • Obtain triphasic abdominal CT as first-line imaging to detect fluid collections, ductal dilation, or fistulous connections 2.
  • Consider ERCP if there is clinical suspicion for bile leak or biliary-enteric fistula 8, 5.
  • Monitor for alarm symptoms including fever, persistent abdominal pain, jaundice, or signs of cholangitis 2, 3.

References

Guideline

Guideline Directed Topic Overview

Dr.Oracle Medical Advisory Board & Editors, 2025

Guideline

Post-Operative Effects of Cholecystectomy

Praxis Medical Insights: Practical Summaries of Clinical Guidelines, 2025

Guideline

Bile Duct Injuries and Complications Following Cholecystectomy

Praxis Medical Insights: Practical Summaries of Clinical Guidelines, 2025

Research

[Pneumobilia. A case report].

Revista medica del Instituto Mexicano del Seguro Social, 2005

Research

Acute emphysematous cholecystitis associated with pneumobilia: a case report.

The Tokai journal of experimental and clinical medicine, 1996

Guideline

Management of Post-Laparoscopic Cholecystectomy Biloma

Praxis Medical Insights: Practical Summaries of Clinical Guidelines, 2025

Professional Medical Disclaimer

This information is intended for healthcare professionals. Any medical decision-making should rely on clinical judgment and independently verified information. The content provided herein does not replace professional discretion and should be considered supplementary to established clinical guidelines. Healthcare providers should verify all information against primary literature and current practice standards before application in patient care. Dr.Oracle assumes no liability for clinical decisions based on this content.

Have a follow-up question?

Our Medical A.I. is used by practicing medical doctors at top research institutions around the world. Ask any follow up question and get world-class guideline-backed answers instantly.