Cystoplus: No Evidence for Efficacy in UTI Treatment
There is no published evidence supporting the use of "Cystoplus" for treating urinary tract infections, and it does not appear in any established clinical guidelines or FDA-approved treatments for UTIs.
Why This Product Cannot Be Recommended
The product "Cystoplus" with unknown ingredients has zero representation in peer-reviewed medical literature or clinical practice guidelines for UTI treatment 1.
Without knowing the specific ingredients, it is impossible to assess efficacy, safety, or appropriate dosing for bacterial urinary tract infections 1.
Established first-line treatments for uncomplicated cystitis include fosfomycin trometamol (3g single dose), nitrofurantoin (100mg twice daily for 5 days), and pivmecillinam (400mg three times daily for 3-5 days) 1.
Products That May Be Confused With "Cystoplus"
If you are referring to products containing glycosaminoglycans (GAGs) like chondroitin sulfate and hyaluronic acid:
CystoProtek (not "Cystoplus") is a dietary supplement studied for interstitial cystitis/painful bladder syndrome, NOT bacterial UTIs 2, 3.
One study showed intravesical instillation of hyaluronic acid plus chondroitin sulfate reduced recurrent bacterial cystitis more effectively than antibiotic prophylaxis (36.7% vs 21.0% UTI-free at 12 months, p=0.03) 4.
However, this was for prevention of recurrent infections through bladder instillation, not oral treatment of active bacterial UTIs 4.
What You Should Use Instead
For acute uncomplicated cystitis in women:
- Fosfomycin trometamol 3g single dose is recommended as first-line therapy 1.
- Nitrofurantoin 100mg twice daily for 5 days is equally effective 1.
- Trimethoprim-sulfamethoxazole 160/800mg twice daily for 3 days only if local E. coli resistance is <20% 1.
For complicated UTIs or pyelonephritis:
- Ciprofloxacin 500mg twice daily for 7 days if fluoroquinolone resistance is <10% 1.
- Ceftriaxone 1g IV as initial dose followed by oral fluoroquinolone if resistance exceeds 10% 1.
Critical Pitfall to Avoid
Do not delay appropriate antibiotic therapy for bacterial UTIs by using unproven supplements or products without established efficacy 1. Untreated or inadequately treated UTIs can progress to pyelonephritis, sepsis, and permanent renal damage 1.