Treatment for Umbilical Drainage
For umbilical drainage with odor or signs of infection, cleanse the area with an antiseptic solution such as povidone-iodine or 4% chlorhexidine, avoid topical antibiotic ointments, and initiate systemic antibiotics if there is periumbilical erythema, purulent discharge, or systemic signs of infection. 1, 2
Initial Assessment and Pathogen Identification
- Umbilical discharge with odor typically indicates bacterial infection, most commonly caused by Staphylococcus aureus, group A and B Streptococci, and Gram-negative organisms including E. coli, Klebsiella, and Pseudomonas species 1, 2
- Examine for severity indicators including periumbilical erythema, tenderness, purulent or bloody discharge, foul smell, and systemic signs such as fever or lethargy 1, 2
- Grade the infection severity from Grade 1 (localized funisitis) to Grade 4 (necrotizing fasciitis) to determine treatment intensity 2
Treatment Algorithm Based on Severity
Mild Localized Infection (Grade 1)
- Apply topical antiseptics such as aqueous chlorhexidine 0.05% or povidone-iodine to the infected area twice daily until resolution 2
- Keep the umbilical area thoroughly dried after bathing and between antiseptic applications 1, 2
- Obtain bacterial swabs to identify the causative organism 2
Moderate to Severe Infection (Grades 2-4)
- Hospitalize immediately and initiate empiric intravenous antibiotics covering S. aureus, Streptococci, and Gram-negative bacilli 2
- Provide aggressive fluid resuscitation if systemic signs are present 2
- Cleanse with povidone-iodine (avoiding tincture of iodine in neonates due to potential thyroid effects) 1, 2
- Consider twice-daily application of chlorhexidine antiseptic until complete resolution 2
Critical Management Principles
What NOT to Do
- Do not apply topical antibiotic ointments or creams to the umbilical area, as they promote fungal infections and antimicrobial resistance 1, 3, 2
- Never delay systemic antibiotics if periumbilical cellulitis or systemic signs are present, as this can lead to high case-fatality rates 2
Special Considerations for Umbilical Catheters
- Remove umbilical catheters immediately if any signs of catheter-related bloodstream infection, vascular insufficiency, or thrombosis are present 1, 3, 2
- Do not replace the catheter once removed in the setting of infection 2
- Umbilical artery catheters should not remain in place for more than 5 days, while umbilical venous catheters can be used for up to 14 days if managed aseptically 3
Neonatal-Specific Recommendations
- For hospital births or settings with low neonatal mortality, use dry cord care 1
- For home births or settings with high neonatal mortality, apply 4% chlorhexidine solution or gel to the umbilical cord stump within 24 hours after birth 1
Common Pitfalls to Avoid
- Avoid using tincture of iodine in neonates due to potential thyroid effects; use povidone-iodine instead 1, 2
- Do not underestimate bloody, foul-smelling discharge—this indicates significant bacterial infection requiring aggressive treatment 2
- Ensure complete drying of the umbilical area after cleansing, as moisture promotes bacterial growth 1, 2