What is the cause of a swollen and painful submandibular (under the chin) lymph node?

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Differential Diagnosis for a Swollen and Painful Lymph Node Under the Chin

Single Most Likely Diagnosis

  • Viral Pharyngitis: This is the most common cause of a swollen and painful lymph node under the chin, often resulting from a viral infection such as the common cold or mononucleosis. The proximity of the lymph node to the throat makes it a likely site for reactive lymphadenopathy in response to a viral pharyngitis.

Other Likely Diagnoses

  • Dental Infection: Infections of the teeth or gums can cause lymphadenopathy in the submandibular region due to the direct drainage of bacteria from the oral cavity to these lymph nodes.
  • Bacterial Pharyngitis: Similar to viral pharyngitis, bacterial infections of the throat, such as streptococcal pharyngitis, can cause swollen and painful lymph nodes under the chin.
  • Cat Scratch Disease: Caused by Bartonella henselae, this condition typically results from a cat scratch or bite and can lead to lymphadenopathy, often in the neck.

Do Not Miss Diagnoses

  • Lymphoma: Although less common, lymphoma (both Hodgkin and non-Hodgkin) can present with lymphadenopathy and must be considered to avoid delayed diagnosis and treatment.
  • Tuberculosis: TB can cause lymphadenitis, particularly in the cervical lymph nodes, and is crucial to diagnose due to its public health implications and the need for specific treatment.
  • Metastatic Cancer: Cancer that has spread to the lymph nodes from a primary site, such as the oral cavity, thyroid, or skin, is a critical diagnosis not to miss due to its significant impact on treatment and prognosis.

Rare Diagnoses

  • Sarcoidosis: A systemic granulomatous disease that can affect any organ, including the lymph nodes, leading to lymphadenopathy.
  • Kikuchi-Fujimoto Disease: A rare, self-limiting condition that causes lymphadenitis, typically in the cervical region, and is more common in young women.
  • Kimura Disease: A chronic inflammatory disorder that can cause lymphadenopathy and eosinophilia, more commonly seen in Asian males.

Professional Medical Disclaimer

This information is intended for healthcare professionals. Any medical decision-making should rely on clinical judgment and independently verified information. The content provided herein does not replace professional discretion and should be considered supplementary to established clinical guidelines. Healthcare providers should verify all information against primary literature and current practice standards before application in patient care. Dr.Oracle assumes no liability for clinical decisions based on this content.

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