How long should irrigation be performed after a Transurethral Resection of the Prostate (TURP)?

Medical Advisory BoardAll articles are reviewed for accuracy by our Medical Advisory Board
Educational purpose only • Exercise caution as content is pending human review
Article Review Status
Submitted
Under Review
Approved

Last updated: December 16, 2025View editorial policy

Personalize

Help us tailor your experience

Which best describes you? Your choice helps us use language that's most understandable for you.

Duration of Bladder Irrigation After TURP

Bladder irrigation after classic TURP should be discontinued when urine is clear or minimally blood-stained, typically within 24 hours, with catheter removal attempted at that time in uncomplicated cases.

Immediate Post-Operative Period (0-24 Hours)

  • Continuous bladder irrigation should be maintained until urine clears, which typically occurs within the first 24 hours in most patients undergoing TURP for mild to moderate prostatic enlargement 1
  • A large-caliber urethral catheter (20-24 Fr) should be placed to facilitate adequate drainage and prevent clot retention 2
  • Irrigation can be maintained through diuretics given at operation or short-term saline irrigation in the operating theater 1
  • Crystalloid administration should be maintained at 1-4 ml/kg/hr during the procedure, with goal-directed fluid boluses for patients developing intravascular volume deficits 3

Criteria for Discontinuing Irrigation

  • Irrigation should be stopped when urine becomes clear or minimally blood-stained, allowing for catheter removal trial at 24 hours 1
  • In a prospective study of 65 patients, 62 patients (95%) who had clear or minimally blood-stained urine successfully voided after catheter removal at 24 hours, with only 2 failures 1
  • Approximately 17-26% of patients may develop clot retention requiring irrigation for 12-24 hours before attempting catheter removal 1

Extended Irrigation Requirements

  • Patients who develop clot retention should receive bladder irrigation for 12-24 hours until urine clears before attempting catheter removal 1
  • Regular monitoring of vital signs, urine output, and fluid balance is essential during the procedure and immediate post-operative period 3
  • Avoid excessive fluid administration to prevent fluid overload and pulmonary edema, especially in patients with cardiac or renal comorbidities 3

Post-Catheter Removal Management

  • Patients should maintain high fluid intake for 3 weeks after TURP, as gross hematuria typically ceases in 47% at 1 week, 73% at 2 weeks, and 96% at 3 weeks 4
  • The duration of postoperative bleeding is directly related to the weight of tissue resected and operation duration 4
  • Patients who continue to bleed beyond 3 weeks should be advised to continue high-fluid intake until urine is completely clear 4

Important Caveats

  • Early catheter removal (24 hours) is feasible for mild to moderate prostatic enlargement (<25g) without significantly increasing complications 1
  • Patients can be discharged after 1-2 successful voidings on the same day of catheter removal in uncomplicated cases 1
  • The choice of irrigation fluid (glycine vs. sterile distilled water) does not significantly affect the frequency of postoperative complications like UTI or dilutional hyponatremia 5
  • Bipolar TURP has a more favorable perioperative safety profile than monopolar TURP, partly due to different irrigation fluid requirements and lower absorption risks 3

References

Guideline

Management of Bladder Perforation During TURBT

Praxis Medical Insights: Practical Summaries of Clinical Guidelines, 2025

Guideline

Irrigation Fluid Management in Transurethral Resection of the Prostate

Praxis Medical Insights: Practical Summaries of Clinical Guidelines, 2025

Professional Medical Disclaimer

This information is intended for healthcare professionals. Any medical decision-making should rely on clinical judgment and independently verified information. The content provided herein does not replace professional discretion and should be considered supplementary to established clinical guidelines. Healthcare providers should verify all information against primary literature and current practice standards before application in patient care. Dr.Oracle assumes no liability for clinical decisions based on this content.

Have a follow-up question?

Our Medical A.I. is used by practicing medical doctors at top research institutions around the world. Ask any follow up question and get world-class guideline-backed answers instantly.