What are the blood sugar hold parameters for Fiasp (insulin aspart)

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Last updated: December 16, 2025View editorial policy

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Blood Sugar Hold Parameters for Fiasp (Insulin Aspart)

Hold Fiasp when blood glucose is <70 mg/dL (3.9 mmol/L) until glucose recovers to safe levels. 1

Primary Hold Threshold

  • Blood glucose <70 mg/dL (3.9 mmol/L) is the absolute hold parameter for Fiasp, as this represents Level 1 hypoglycemia requiring immediate intervention. 2, 3, 1
  • This threshold aligns with the standard definition of hypoglycemia in both outpatient and inpatient settings, correlating with the initial release of counterregulatory hormones. 2

Clinical Action Points for Insulin Modification

Blood glucose <100 mg/dL should trigger reassessment of the insulin regimen, as fasting glucose below this level predicts hypoglycemia within the next 24 hours. 3

  • Blood glucose <70 mg/dL (3.9 mmol/L) requires modification of the insulin regimen unless the hypoglycemic event is easily explained by other factors such as a missed meal. 2, 3
  • More severe hypoglycemia thresholds include Level 2 (<54 mg/dL or 3.0 mmol/L) and Level 3 (any level with altered mental/physical functioning requiring assistance). 2, 3

Special Circumstances Requiring Hold

Hold Fiasp if the patient cannot maintain oral intake due to persistent vomiting or diarrhea preventing food consumption. 1

  • If a patient has already taken their Fiasp dose but then becomes unable to eat, provide 4-8 oz of juice or soda immediately to prevent severe hypoglycemia rather than simply holding the next dose. 1
  • The rapid onset of Fiasp (5 minutes) means hypoglycemia can develop quickly, giving less time to recognize symptoms compared to regular insulin. 1

Monitoring Requirements When Approaching Hold Parameters

  • Recheck glucose in 15-20 minutes after treating hypoglycemia <70 mg/dL. 1
  • Patients receiving insulin should perform more frequent self-monitoring (every 4-6 hours) during illness or when glucose values are unstable. 1
  • Check ketones if unable to eat or if blood glucose remains elevated despite insulin. 1

Common Pitfalls to Avoid

Never continue Fiasp if the patient has taken their dose but then becomes unable to eat—this is a critical error that can lead to severe hypoglycemia requiring immediate carbohydrate administration. 1

  • During illness, if blood glucose is more elevated than usual, consider an empirical 10-20% increase in insulin doses rather than automatically holding, but only if the patient can maintain oral intake. 1
  • Document all hypoglycemic episodes in the medical record, including duration, associated symptoms, amount of glucose administered, and the next blood glucose concentration. 3

References

Guideline

Management of NovoLog (Insulin Aspart) Therapy

Praxis Medical Insights: Practical Summaries of Clinical Guidelines, 2025

Guideline

Guideline Directed Topic Overview

Dr.Oracle Medical Advisory Board & Editors, 2025

Guideline

Hypoglycemia Management in Critically Ill Patients

Praxis Medical Insights: Practical Summaries of Clinical Guidelines, 2025

Professional Medical Disclaimer

This information is intended for healthcare professionals. Any medical decision-making should rely on clinical judgment and independently verified information. The content provided herein does not replace professional discretion and should be considered supplementary to established clinical guidelines. Healthcare providers should verify all information against primary literature and current practice standards before application in patient care. Dr.Oracle assumes no liability for clinical decisions based on this content.

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