What is the management for drug-induced burn or burning sensation?

Medical Advisory BoardAll articles are reviewed for accuracy by our Medical Advisory Board
Educational purpose only • Exercise caution as content is pending human review
Article Review Status
Submitted
Under Review
Approved

Last updated: February 13, 2025View editorial policy

Personalize

Help us tailor your experience

Which best describes you? Your choice helps us use language that's most understandable for you.

From the Guidelines

Drug-induced burn or burning sensation should be managed with over-the-counter analgesics such as acetaminophen or NSAIDs.

Management Options

  • Over-the-counter analgesics like acetaminophen or NSAIDs are well-tolerated and generally recommended for burn pain, as seen in a prospective study where 61 patients with second- or third-degree burns were randomly assigned to receive 800 mg IV ibuprofen or placebo every 6 hours with no significant incidence of serious adverse events 1.
  • Ketamine is an effective drug for burn-induced pain and can limit morphine consumption, especially for short-lasting pain induced by burns or dressing changes 1.
  • Short-acting opioids and inhaled nitrous oxide can be useful, especially when no intravenous access is available 1.

Non-Pharmacological Treatments

  • Cooling limited burned surfaces and covering burns with a fatty substance (e.g., Vaseline and dressings) might improve pain control 1.
  • Virtual reality or hypnosis techniques may reduce the intensity of pain and the patient’s anxiety 1.

Special Considerations

  • Patients with severe burns, especially those involving the face, hands, feet, and genitals, or those with a large surface area, may require specialized burn center treatment due to the likely need for intravenous fluid resuscitation, surgery, and other specialized treatments 1.

From the Research

Management of Drug-Induced Burn or Burning Sensation

  • The management of burn injury, including drug-induced burn or burning sensation, has seen significant advances in recent years, with a focus on proactive approaches to solve old problems 2.
  • Burn pain can be managed through a combination of pharmacological and non-pharmacological interventions, including the use of opioids, local blocks, and general anesthesia, as well as non-pharmacologic approaches such as hypnosis, auricular electrical stimulation, and massage therapy 3, 4.
  • The treatment of burn pain should be tailored to the individual patient's needs, taking into account the severity and type of pain, as well as the patient's medical history and other factors 3, 4, 5.
  • A stepwise algorithm approach to multimodal pharmacologic management can be effective in managing burn-related pain, with combination therapies increasing efficacy and reducing toxicity 5.
  • It is essential to assess burn-related pain by chronicity (acute or chronic) and type (nociceptive, neuropathic, nociplastic) to guide pharmacologic management 5.
  • In some cases, surgical interventions may be necessary to manage burn-related pain, and referral to a pain management specialist may be indicated 5.

References

Guideline

Guideline Directed Topic Overview

Dr.Oracle Medical Advisory Board & Editors, 2025

Research

Burns: what are the pharmacological treatment options?

Expert opinion on pharmacotherapy, 2008

Research

Treatment of pain in severe burns.

American journal of clinical dermatology, 2000

Research

Management of pain after burn injury.

Current opinion in anaesthesiology, 2002

Professional Medical Disclaimer

This information is intended for healthcare professionals. Any medical decision-making should rely on clinical judgment and independently verified information. The content provided herein does not replace professional discretion and should be considered supplementary to established clinical guidelines. Healthcare providers should verify all information against primary literature and current practice standards before application in patient care. Dr.Oracle assumes no liability for clinical decisions based on this content.

Have a follow-up question?

Our Medical A.I. is used by practicing medical doctors at top research institutions around the world. Ask any follow up question and get world-class guideline-backed answers instantly.