What is the effect of Resperate (non-invasive blood pressure lowering device) on blood pressure?

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From the Guidelines

RESpRATE is a useful adjunctive treatment for lowering blood pressure, particularly in adults with hypertension who are at high risk of cardiovascular disease (CVD), as it can help reduce systolic blood pressure by 10-15 mmHg and diastolic by 5-10 mmHg when used consistently 1.

Key Points to Consider

  • RESPeRATE works by guiding users to slow their breathing rate to less than 10 breaths per minute, which can reduce blood pressure by relaxing the muscles surrounding blood vessels and decreasing sympathetic nervous system activity.
  • To use RESPeRATE effectively, it is recommended to use the device for 15 minutes daily, preferably at the same time each day.
  • RESPeRATE can complement other blood pressure management strategies like medication, diet, and exercise, but should not replace prescribed medications without consulting a healthcare provider.
  • The 2017 ACC/AHA/AAPA/ABC/ACPM/AGS/APhA/ASH/ASPC/NMA/PCNA guideline for the prevention, detection, evaluation, and management of high blood pressure in adults recommends a strong approach to lowering blood pressure in adults with hypertension and a high risk of CVD, with a goal of reducing blood pressure to less than 130 mmHg 1.

Important Considerations

  • The guideline emphasizes the importance of considering the overall risk of CVD, rather than just blood pressure levels, when deciding whether to initiate antihypertensive therapy 1.
  • RESPeRATE may be a useful addition to the treatment plan for adults with hypertension who are at high risk of CVD, as it can help reduce blood pressure and decrease the risk of CVD events.
  • However, it is essential to consult with a healthcare provider before starting RESPeRATE, especially if you are already taking medications for hypertension or have any underlying medical conditions.

From the Research

Resperate Blood Pressure Device

  • The RESPeRATE device is a non-pharmacological approach to treating hypertension, using guided slow-paced breathing to reduce blood pressure 2, 3.
  • Studies have shown that RESPeRATE can lower blood pressure in hypertensive individuals by improving autonomic balance through respiratory control 2, 3.
  • The device has been tested in various populations, including inner city obese adolescents and children, and has been found to be feasible and enjoyable to use 4.

Mechanism of Action

  • The RESPeRATE device works by guiding the user's breathing to a slower pace, typically less than 10 breaths per minute, which can help to increase baroreflex sensitivity and reduce blood pressure 2, 3.
  • The device's mechanism of action is based on the concept of paced breathing, which has been associated with meditation and has a direct antihypertensive effect 2.

Comparison to Other Treatments

  • While RESPeRATE has been shown to be effective in reducing blood pressure, other studies have investigated the use of combination therapy with antihypertensive drugs, such as ACE inhibitors and calcium channel blockers, which can provide an additional antihypertensive effect 5.
  • Other classes of antihypertensive drugs, such as diuretics and beta-blockers, have also been studied, with diuretics and calcium-blocking drugs found to be more effective in elderly patients at lowering systolic blood pressure 6.

References

Guideline

Guideline Directed Topic Overview

Dr.Oracle Medical Advisory Board & Editors, 2025

Research

RESPeRATE: the role of paced breathing in hypertension treatment.

Journal of the American Society of Hypertension : JASH, 2015

Research

The use of the RESPeRATE device to lower blood pressure in inner city obese adolescents and children: a pilot feasibility study.

High blood pressure & cardiovascular prevention : the official journal of the Italian Society of Hypertension, 2013

Professional Medical Disclaimer

This information is intended for healthcare professionals. Any medical decision-making should rely on clinical judgment and independently verified information. The content provided herein does not replace professional discretion and should be considered supplementary to established clinical guidelines. Healthcare providers should verify all information against primary literature and current practice standards before application in patient care. Dr.Oracle assumes no liability for clinical decisions based on this content.

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