Apoptolive Dosing Information Not Available in Medical Literature
There is no established medical evidence or guideline recommendations for a product called "Apoptolive" as a liver support supplement. The term does not appear in any peer-reviewed medical literature, FDA-approved drug databases, or clinical practice guidelines for liver disease management.
Critical Context
The provided evidence contains no information about "Apoptolive" dosing or use. The search results discuss:
- Apoptosis mechanisms in liver disease 1, 2, 3, 4 - These are cellular death pathways, not a therapeutic agent
- Standard liver disease treatments including ursodiol (13-15 mg/kg/day for primary biliary cirrhosis) 5, nutritional support (1.2-1.5 g/kg/day protein, 35-40 kcal/kg/day) 6, and corticosteroids for alcoholic hepatitis 6
- Unrelated medications such as tuberculosis drugs 6, anticoagulants 6, and obesity medications 6
Evidence-Based Liver Support Recommendations
For patients with liver conditions requiring nutritional support, the Korean Association for the Study of the Liver recommends:
- Protein intake: 1.2-1.5 g/kg/day (or 1.5 g/kg/day in critically ill patients) 6
- Caloric intake: 35-40 kcal/kg/day (or 40 kcal/kg/day in critically ill patients) 6
- Vitamin and mineral supplementation: Including vitamin A, thiamine, vitamin B12, folic acid, pyridoxine, vitamin D, and zinc for patients with nutritional deficiency 6
For specific liver conditions:
- Primary biliary cirrhosis: Ursodiol 13-15 mg/kg/day 5
- Alcoholic liver disease: Alcohol abstinence is the most important treatment, with baclofen and acamprosate as pharmacologic options for achieving abstinence 6
Clinical Recommendation
If you are seeking liver support therapy, consult with a hepatologist regarding evidence-based treatments rather than unverified supplements. The absence of "Apoptolive" from medical literature raises concerns about its regulatory status, safety profile, and efficacy claims. Standard liver disease management should follow established guidelines from organizations like the American Association for the Study of Liver Diseases or the European Association for the Study of the Liver 5.