What is the role of Artificial Intelligence (AI) in regional anesthesia?

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Last updated: December 17, 2025View editorial policy

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Artificial Intelligence in Regional Anesthesia

AI-assisted ultrasound guidance systems improve image acquisition and anatomical structure identification for regional anesthesia, particularly benefiting non-expert practitioners, though clinical outcome data and widespread adoption remain limited.

Current Applications of AI in Regional Anesthesia

Ultrasound Image Optimization and Interpretation

AI technology has demonstrated measurable improvements in ultrasound-guided regional anesthesia (UGRA) performance:

  • Non-experts achieved correct block view acquisition in 90.3% of scans with AI assistance versus 75.1% without AI (p=0.031), and correctly identified anatomical structures 88.8% of the time with AI versus 77.4% without (p=0.002). 1

  • AI devices apply real-time color overlays on ultrasound images to highlight key anatomical structures including nerves, vessels, and surrounding tissues, functioning as an assistive tool during scanning. 2

  • The technology shows particular utility for anatomical landmark identification across nine peripheral nerve block regions, potentially reducing complications from misidentification of safety structures. 3, 2

Training and Education Enhancement

AI-assisted systems demonstrate differential benefits based on practitioner experience level:

  • Non-experts provided positive feedback most frequently regarding AI's role in training (61.7%), while experts valued its utility for teaching (50%). 2

  • The technology may accelerate the learning curve for UGRA by providing immediate visual feedback during skill acquisition, potentially expanding patient access to regional anesthesia techniques in settings with limited expert availability. 1

  • AI could transform anesthesia education through authentic lifelike training simulations and individualized student feedback systems, though these applications remain largely theoretical. 4

Specific Technical Applications

Needle Visualization and Tracking

  • AI solutions can improve visualization of needle advancement during block performance and monitor local anesthetic injection spread, addressing one of the most challenging technical aspects of UGRA. 3

  • The technology assists in real-time needle tracking, which is particularly valuable for in-plane needling techniques where maintaining needle tip visualization within the ultrasound beam is critical. 3

Safety Structure Protection

  • Expert reviewers identified potentially increased risk in only 4.7% of AI-assisted scans performed by non-experts, suggesting the technology does not substantially increase the risk of needle trauma to safety structures like vessels or pleura. 2

  • AI systems can highlight safety structures (arteries, veins, pleura) in contrasting colors, providing continuous awareness of structures to avoid during needle advancement. 3, 2

Current Limitations and Challenges

Evidence Quality Gaps

Randomized controlled trials demonstrating improved clinical outcomes (pain scores, block success rates, complication rates, patient satisfaction) are completely absent from the current literature. 3

  • All existing evidence comes from exploratory studies, feasibility assessments, and performance evaluations in controlled settings rather than real-world clinical practice. 3, 2, 1

  • No studies have demonstrated that AI-assisted UGRA reduces major complications such as local anesthetic systemic toxicity, nerve injury, or pneumothorax compared to standard ultrasound guidance. 3

Technical and Implementation Barriers

  • Data quantity and quality issues limit AI system development, along with technical limitations in real-time processing and image interpretation accuracy across different ultrasound machines and settings. 4

  • Moral and ethical dilemmas regarding liability, clinical decision-making authority, and the appropriate role of AI assistance versus human expertise remain unresolved. 4

  • The technology requires validation across different patient populations, body habitus variations, and clinical workflows before widespread adoption can be recommended. 5

Integration with Existing Guidelines

Ergonomic Considerations

  • AI-assisted systems must be integrated with established ergonomic principles for ultrasound-guided procedures, including proper machine positioning, monitor height adjustment, and maintenance of neutral wrist position during probe handling. 6

  • The addition of AI overlay technology should not compromise the fundamental ergonomic setup that prevents musculoskeletal disorders in practitioners performing regional blocks. 6

Clinical Context Appropriateness

  • AI assistance is most relevant for procedures requiring precise anatomical identification, such as peripheral nerve blocks for lower extremity trauma, where accurate needle placement is critical. 6

  • The technology does not replace clinical judgment regarding when regional anesthesia is appropriate versus general anesthesia, particularly in settings like endovascular procedures where regional techniques may be unnecessary. 7

Future Directions and Research Needs

Required Clinical Validation

Prospective randomized trials must evaluate whether AI-assisted UGRA improves patient-centered outcomes including block success rates, procedure time, complication rates, and patient satisfaction before routine clinical adoption can be recommended. 3

  • Studies should focus on identifying specific patient populations and block types where AI assistance provides the greatest benefit, rather than assuming universal applicability. 5

  • External validation across different institutions, equipment types, and practitioner experience levels is essential to ensure generalizability. 5

Standardization Requirements

  • Transparent reporting of AI system characteristics, including algorithm identification, training datasets, implementation environment, and user training requirements, must become standard practice. 5

  • Guidelines similar to CONSORT-AI and SPIRIT-AI for clinical trials should be developed specifically for AI-assisted procedural interventions in anesthesiology. 5

Practical Recommendations for Current Practice

  • AI-assisted ultrasound systems may be considered as adjunctive tools for non-expert practitioners learning UGRA or for experts teaching these techniques, but should not replace fundamental ultrasound skills training. 2, 1

  • Practitioners using AI assistance must maintain vigilance for false-positive or false-negative structure identification, as the technology is not infallible and clinical judgment remains paramount. 2

  • Institutions implementing AI-assisted UGRA should establish protocols for system validation, user training, and ongoing quality assessment to ensure patient safety. 4

  • The technology should be viewed as complementary to, not a replacement for, proper patient selection, anatomical knowledge, and technical skill development in regional anesthesia. 3, 4

References

Guideline

Artificial Intelligence in Pediatric Surgery for Improved Patient Outcomes

Praxis Medical Insights: Practical Summaries of Clinical Guidelines, 2025

Guideline

Guideline Directed Topic Overview

Dr.Oracle Medical Advisory Board & Editors, 2025

Guideline

Anesthetic Management for Tibial Angioplasty

Praxis Medical Insights: Practical Summaries of Clinical Guidelines, 2025

Professional Medical Disclaimer

This information is intended for healthcare professionals. Any medical decision-making should rely on clinical judgment and independently verified information. The content provided herein does not replace professional discretion and should be considered supplementary to established clinical guidelines. Healthcare providers should verify all information against primary literature and current practice standards before application in patient care. Dr.Oracle assumes no liability for clinical decisions based on this content.

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