What is the differential diagnosis for a 3-week duration of pharyngitis, accompanied by mild cephalgia and rhinorrhea?

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Differential Diagnosis for 3 Week Sore Throat, Mild Headache, Mild Runny Nose

  • Single Most Likely Diagnosis
    • Viral pharyngitis: This is the most common cause of sore throat and is often accompanied by mild headache and runny nose. The duration of 3 weeks is consistent with a prolonged viral infection.
  • Other Likely Diagnoses
    • Allergic rhinitis: Prolonged exposure to allergens can cause chronic sore throat, headache, and runny nose.
    • Sinusitis: A bacterial or viral infection of the sinuses can cause sore throat, headache, and runny nose, especially if the infection is chronic.
    • Tonsillitis: Inflammation of the tonsils can cause sore throat and may be accompanied by headache and runny nose.
  • Do Not Miss Diagnoses
    • Infectious mononucleosis (mono): Although less common, mono can cause prolonged sore throat, headache, and runny nose, and is important to diagnose due to potential complications.
    • Streptococcal pharyngitis: Although the duration is longer than typical, it's crucial to rule out strep throat due to the risk of rheumatic fever and other complications.
    • Lemierre's syndrome: A rare but life-threatening condition that can cause sore throat, headache, and neck pain, often following a viral pharyngitis.
  • Rare Diagnoses
    • Tuberculosis: Although rare in many areas, TB can cause chronic sore throat, headache, and other systemic symptoms.
    • Sarcoidosis: A systemic disease that can cause a variety of symptoms, including sore throat, headache, and sinusitis.
    • HIV infection: Acute HIV infection can cause a variety of symptoms, including sore throat, headache, and runny nose, and is important to consider in patients with risk factors.

Professional Medical Disclaimer

This information is intended for healthcare professionals. Any medical decision-making should rely on clinical judgment and independently verified information. The content provided herein does not replace professional discretion and should be considered supplementary to established clinical guidelines. Healthcare providers should verify all information against primary literature and current practice standards before application in patient care. Dr.Oracle assumes no liability for clinical decisions based on this content.

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