What is the diagnosis for a 57-year-old female patient with a history of hypertension, acute myeloid leukemia (AML) treated with cytarabine (Cytosine Arabinoside) and daunorubicin, hypothyroidism, and a heart murmur, presenting with progressive chest pressure, extreme fatigue, and tachycardia, exacerbated by physical activity and occurring at rest?

Differential Diagnosis for Ms. Glenda Lamont

Single Most Likely Diagnosis

• Stable Angina: This is the most likely diagnosis given Ms. Lamont's symptoms of chest pressure that worsen with exertion and improve with rest. Her history of hypertension and smoking also increase her risk for coronary artery disease.

Other Likely Diagnoses

• Heart Failure: Ms. Lamont's symptoms of extreme fatigue and chest pressure, especially with exertion, could be indicative of heart failure. Her history of a heart murmur and hypertension also increase her risk for this condition.
• Anxiety or Panic Disorder: Ms. Lamont's description of her heart "beating out of her chest" and feeling anxious could suggest an anxiety or panic disorder, which could be contributing to her chest pressure symptoms.
• Hypothyroidism: Although Ms. Lamont is being treated for hypothyroidism, her symptoms of fatigue and chest pressure could be indicative of inadequate treatment or worsening of her condition.

Do Not Miss Diagnoses

• Acute Coronary Syndrome (ACS): Although Ms. Lamont's symptoms have been ongoing for months, it is still possible that she could be experiencing an ACS, which would require immediate attention.
• Pulmonary Embolism (PE): Ms. Lamont's history of cancer and chemotherapy increase her risk for PE, which could present with chest pressure and shortness of breath.
• Cardiac Tamponade: Ms. Lamont's history of cancer and chemotherapy also increase her risk for cardiac tamponade, which could present with chest pressure and shortness of breath.
• Aortic Dissection: Although less likely, aortic dissection is a life-threatening condition that could present with chest pressure and would require immediate attention.

Rare Diagnoses

• Cardiac Sarcoidosis: Ms. Lamont's history of cancer and chemotherapy increase her risk for cardiac sarcoidosis, which could present with chest pressure and arrhythmias.
• Amyloidosis: Ms. Lamont's history of cancer and chemotherapy also increase her risk for amyloidosis, which could present with chest pressure and shortness of breath.
• Cardiac Lymphoma: Although rare, cardiac lymphoma could present with chest pressure and shortness of breath, and would require immediate attention.