Evaluation of Shoulder Pain
Start with plain radiographs (minimum 3 views: AP, Grashey, and axillary or scapular Y) as the initial imaging for all patients presenting with shoulder pain, regardless of mechanism. 1
Initial Clinical Assessment
Red Flags Requiring Urgent Evaluation
- Fever with joint effusion suggesting septic arthritis 1
- Acute neurologic deficits 1
- Suspected cardiac or pulmonary pathology causing referred pain 1
- Acute trauma with suspected fracture or dislocation 1
Age-Stratified Differential Diagnosis
Patients Under 35 Years:
- Labral tears and glenohumeral instability are the primary concerns 1
- Key historical features include recurrent subluxation, "dead arm" sensation, or mechanical symptoms 1
- Look for Hill-Sachs deformity or bony Bankart lesions on radiographs 1
Patients 35 Years and Older:
- Rotator cuff disease becomes the predominant pathology 1
- Characteristic symptoms include pain with overhead activities, night pain, and weakness with external rotation or abduction 1
- Biceps tendon pathology presents with anterior shoulder pain and positive Speed's or Yergason's test 1
Physical Examination Priorities
- Evaluate tone, strength, soft tissue length changes, and joint alignment of the shoulder girdle 2
- Assess range of motion in all planes, particularly external rotation and abduction 2
- Perform provocative testing for impingement, instability, and specific tendon pathology 1
- Complete sensorimotor examination of the upper extremity to identify neuropathic features 3
Imaging Algorithm After Initial Radiographs
If Fracture Identified:
- Order CT without contrast to characterize fracture complexity, displacement, and aid surgical planning 1
If Suspected Instability/Dislocation:
- MRI without IV contrast is the primary study 1
- Consider CT without contrast when bone loss assessment is critical for surgical planning 1
If Suspected Labral Tear:
- MR arthrography is the reference standard in subacute/chronic settings 1
- MRI without contrast is preferred in acute trauma because hemarthrosis provides natural joint distention 1
If Suspected Rotator Cuff Tear:
- MRI without contrast or ultrasound are equivalent first-line studies 1
- Choice depends on local expertise and availability 1
- Ultrasound may be preferred if significant metallic artifact from prior surgery would limit MRI quality 3
If Suspected Septic Arthritis:
- Ultrasound-guided or fluoroscopy-guided arthrocentesis is the diagnostic procedure of choice 1
Treatment Approach Based on Diagnosis
Conservative Management (First-Line for Most Non-Urgent Pathology)
Pharmacologic Management:
- NSAIDs such as ibuprofen 400-800 mg three to four times daily 1
- Acetaminophen for pain relief when no contraindications exist 2
- Neuromodulating medications (gabapentin or pregabalin) when neuropathic features are present, including electric shock sensations, sensory changes, allodynia, or hyperpathia 3, 1
Physical Therapy:
- Gentle stretching and mobilization techniques for pain related to range of motion limitations, focusing on increasing external rotation and abduction 2
- Active range of motion should be increased gradually while restoring alignment and strengthening weak shoulder girdle muscles 2
- Structured exercise programs with scapular stabilization 3
- Active, active-assisted, or passive range of motion exercises to prevent complex regional pain syndrome 2
Activity Modification:
- Patient education on positioning and ergonomics 1
- Avoid repetitive overhead movements that trigger symptoms during the acute phase 3
Interventional Options After Failed Conservative Management
Injection Therapies:
- Botulinum toxin injections into subscapularis and pectoralis muscles for hemiplegic shoulder pain related to spasticity 2
- Subacromial corticosteroid injections when pain is related to injury or inflammation of the rotator cuff or bursa 2
- Suprascapular nerve blocks 1
Surgical Referral Indications
- Acute fractures requiring fixation 1
- Failed adequate conservative management (typically 6-8 weeks) 1
- Progressive neurological deficits 1
- Severe restrictions in range of motion with muscle contractures 1
Critical Pitfalls to Avoid
- Do not dismiss neuropathic symptoms as "normal postoperative pain"—these require specific evaluation for nerve pathology and targeted treatment with neuromodulating agents rather than just NSAIDs 3
- Do not order MR arthrography in the acute postoperative setting—standard MRI without contrast is sufficient and appropriate 3
- Do not skip initial radiographs—they are essential for all presentations before advanced imaging 1
- Do not delay urgent referral for red flag diagnoses including septic arthritis, acute neurologic deficits, or fractures requiring fixation 1