What is the evaluation and treatment approach for a patient presenting with shoulder pain?

Medical Advisory BoardAll articles are reviewed for accuracy by our Medical Advisory Board
Educational purpose only • Exercise caution as content is pending human review
Article Review Status
Submitted
Under Review
Approved

Last updated: December 17, 2025View editorial policy

Personalize

Help us tailor your experience

Which best describes you? Your choice helps us use language that's most understandable for you.

Evaluation of Shoulder Pain

Start with plain radiographs (minimum 3 views: AP, Grashey, and axillary or scapular Y) as the initial imaging for all patients presenting with shoulder pain, regardless of mechanism. 1

Initial Clinical Assessment

Red Flags Requiring Urgent Evaluation

  • Fever with joint effusion suggesting septic arthritis 1
  • Acute neurologic deficits 1
  • Suspected cardiac or pulmonary pathology causing referred pain 1
  • Acute trauma with suspected fracture or dislocation 1

Age-Stratified Differential Diagnosis

Patients Under 35 Years:

  • Labral tears and glenohumeral instability are the primary concerns 1
  • Key historical features include recurrent subluxation, "dead arm" sensation, or mechanical symptoms 1
  • Look for Hill-Sachs deformity or bony Bankart lesions on radiographs 1

Patients 35 Years and Older:

  • Rotator cuff disease becomes the predominant pathology 1
  • Characteristic symptoms include pain with overhead activities, night pain, and weakness with external rotation or abduction 1
  • Biceps tendon pathology presents with anterior shoulder pain and positive Speed's or Yergason's test 1

Physical Examination Priorities

  • Evaluate tone, strength, soft tissue length changes, and joint alignment of the shoulder girdle 2
  • Assess range of motion in all planes, particularly external rotation and abduction 2
  • Perform provocative testing for impingement, instability, and specific tendon pathology 1
  • Complete sensorimotor examination of the upper extremity to identify neuropathic features 3

Imaging Algorithm After Initial Radiographs

If Fracture Identified:

  • Order CT without contrast to characterize fracture complexity, displacement, and aid surgical planning 1

If Suspected Instability/Dislocation:

  • MRI without IV contrast is the primary study 1
  • Consider CT without contrast when bone loss assessment is critical for surgical planning 1

If Suspected Labral Tear:

  • MR arthrography is the reference standard in subacute/chronic settings 1
  • MRI without contrast is preferred in acute trauma because hemarthrosis provides natural joint distention 1

If Suspected Rotator Cuff Tear:

  • MRI without contrast or ultrasound are equivalent first-line studies 1
  • Choice depends on local expertise and availability 1
  • Ultrasound may be preferred if significant metallic artifact from prior surgery would limit MRI quality 3

If Suspected Septic Arthritis:

  • Ultrasound-guided or fluoroscopy-guided arthrocentesis is the diagnostic procedure of choice 1

Treatment Approach Based on Diagnosis

Conservative Management (First-Line for Most Non-Urgent Pathology)

Pharmacologic Management:

  • NSAIDs such as ibuprofen 400-800 mg three to four times daily 1
  • Acetaminophen for pain relief when no contraindications exist 2
  • Neuromodulating medications (gabapentin or pregabalin) when neuropathic features are present, including electric shock sensations, sensory changes, allodynia, or hyperpathia 3, 1

Physical Therapy:

  • Gentle stretching and mobilization techniques for pain related to range of motion limitations, focusing on increasing external rotation and abduction 2
  • Active range of motion should be increased gradually while restoring alignment and strengthening weak shoulder girdle muscles 2
  • Structured exercise programs with scapular stabilization 3
  • Active, active-assisted, or passive range of motion exercises to prevent complex regional pain syndrome 2

Activity Modification:

  • Patient education on positioning and ergonomics 1
  • Avoid repetitive overhead movements that trigger symptoms during the acute phase 3

Interventional Options After Failed Conservative Management

Injection Therapies:

  • Botulinum toxin injections into subscapularis and pectoralis muscles for hemiplegic shoulder pain related to spasticity 2
  • Subacromial corticosteroid injections when pain is related to injury or inflammation of the rotator cuff or bursa 2
  • Suprascapular nerve blocks 1

Surgical Referral Indications

  • Acute fractures requiring fixation 1
  • Failed adequate conservative management (typically 6-8 weeks) 1
  • Progressive neurological deficits 1
  • Severe restrictions in range of motion with muscle contractures 1

Critical Pitfalls to Avoid

  • Do not dismiss neuropathic symptoms as "normal postoperative pain"—these require specific evaluation for nerve pathology and targeted treatment with neuromodulating agents rather than just NSAIDs 3
  • Do not order MR arthrography in the acute postoperative setting—standard MRI without contrast is sufficient and appropriate 3
  • Do not skip initial radiographs—they are essential for all presentations before advanced imaging 1
  • Do not delay urgent referral for red flag diagnoses including septic arthritis, acute neurologic deficits, or fractures requiring fixation 1

References

Guideline

Diagnostic Approach to Shoulder Pain

Praxis Medical Insights: Practical Summaries of Clinical Guidelines, 2025

Guideline

Guideline Directed Topic Overview

Dr.Oracle Medical Advisory Board & Editors, 2025

Guideline

Management of Post-Surgical Shoulder Pain with Neuropathic Features

Praxis Medical Insights: Practical Summaries of Clinical Guidelines, 2025

Professional Medical Disclaimer

This information is intended for healthcare professionals. Any medical decision-making should rely on clinical judgment and independently verified information. The content provided herein does not replace professional discretion and should be considered supplementary to established clinical guidelines. Healthcare providers should verify all information against primary literature and current practice standards before application in patient care. Dr.Oracle assumes no liability for clinical decisions based on this content.

Have a follow-up question?

Our Medical A.I. is used by practicing medical doctors at top research institutions around the world. Ask any follow up question and get world-class guideline-backed answers instantly.