How do I treat an open boil?

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Last updated: December 17, 2025View editorial policy

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Treatment of an Open Boil (Furuncle)

Incision and drainage is the primary and definitive treatment for boils, and antibiotics are typically unnecessary unless specific high-risk features are present. 1

Primary Treatment: Incision and Drainage

  • The most important therapy is to open the boil, evacuate the infected material, and continue dressing changes until the wound heals by secondary intention. 2
  • Simply covering the surgical site with a dry dressing is usually the most effective treatment of the wound after drainage. 2
  • Obtain Gram stain and culture of the pus during drainage, though treatment without these studies is reasonable in typical cases. 1
  • For large boils that are troublesome or interfere with function, pierce them with a sterile needle to release fluid while leaving the blister roof in place as a biological dressing. 2

When Antibiotics Are NOT Needed

  • If there is <5 cm of erythema and induration around the boil, and the patient has minimal systemic signs (temperature <38.5°C, WBC count <12,000 cells/µL, pulse <100 beats/minute), antibiotics are unnecessary. 2
  • Studies of subcutaneous abscesses found little or no benefit for antibiotics when combined with drainage. 2
  • Incision and drainage of superficial abscesses rarely causes bacteremia, so prophylactic antibiotics are not recommended. 2

When to Add Antibiotics to Incision and Drainage

Add antibiotics directed against S. aureus when ANY of the following are present: 1

  • Temperature >38.5°C or heart rate >110 beats/minute 2, 1
  • Erythema extending >5 cm beyond the wound margins 2, 1
  • Systemic inflammatory response syndrome (SIRS) 1
  • Severe or extensive disease with rapid progression 1
  • Markedly impaired host defenses or immunocompromised status 1
  • Extremes of age 1
  • Difficult to drain locations 1
  • Associated septic phlebitis 1
  • Lack of response to incision and drainage alone 1

Antibiotic Selection When Indicated

  • Empirical coverage for community-acquired MRSA (CA-MRSA) is recommended pending culture results. 1
  • Treatment options include: clindamycin, trimethoprim-sulfamethoxazole (TMP-SMX), tetracyclines (doxycycline or minocycline), or linezolid. 1
  • Adjust antibiotic therapy based on culture results. 3
  • Do NOT use rifampin as a single agent or adjunctive therapy for boils. 1

Duration of Treatment

  • When antibiotics are used, prescribe 5 to 10 days of therapy based on clinical response. 1
  • Evaluate for clinical improvement (decreased pain and swelling) within 48-72 hours after treatment. 3

Wound Care After Drainage

  • After drainage, apply a bland emollient such as 50% white soft paraffin and 50% liquid paraffin to support barrier function and encourage re-epithelialization. 2
  • Alternatively, apply a small amount of topical antibiotic ointment (bacitracin or triple antibiotic) 1 to 3 times daily and cover with a sterile bandage. 4, 5
  • For extensive areas of erosion, antiseptics such as potassium permanganate baths or antiseptic-containing bath oils may be used for a few days to dry lesions and prevent infection. 2
  • Painful areas may be covered with a low-adhesion dressing such as Mepitel or Atrauman held in place with soft elasticated viscose. 2

Management of Recurrent Boils

  • Search for local causes such as pilonidal cyst, hidradenitis suppurativa, or foreign material at sites of recurrent infection. 1
  • Culture recurrent abscesses early in the course of infection. 1
  • Consider a 5-day decolonization regimen including intranasal mupirocin, daily chlorhexidine washes, and daily decontamination of personal items for patients with recurrent S. aureus boils. 1
  • Treat with a 5- to 10-day course of an antibiotic active against the isolated pathogen. 1
  • Risk factors for recurrence include obesity, diabetes, age <30 years, smoking, and prior antibiotic use. 6

Critical Pitfalls to Avoid

  • Do not routinely prescribe antibiotics without incision and drainage—antibiotics without drainage are ineffective as the primary treatment. 1
  • Avoid ultrasonographically guided needle aspiration, as it was successful in only 25% of cases overall and <10% with MRSA infections. 1
  • Never attempt home lancing with non-sterile instruments (e.g., hot needles), as this can lead to severe invasive infection including osteomyelitis and sepsis. 7

References

Guideline

Treatment of Boils (Furuncles) with Antibiotics

Praxis Medical Insights: Practical Summaries of Clinical Guidelines, 2025

Guideline

Guideline Directed Topic Overview

Dr.Oracle Medical Advisory Board & Editors, 2025

Guideline

Treatment of Skene's Gland Infections and Abscesses

Praxis Medical Insights: Practical Summaries of Clinical Guidelines, 2025

Research

Incidence and recurrence of boils and abscesses within the first year: a cohort study in UK primary care.

The British journal of general practice : the journal of the Royal College of General Practitioners, 2015

Professional Medical Disclaimer

This information is intended for healthcare professionals. Any medical decision-making should rely on clinical judgment and independently verified information. The content provided herein does not replace professional discretion and should be considered supplementary to established clinical guidelines. Healthcare providers should verify all information against primary literature and current practice standards before application in patient care. Dr.Oracle assumes no liability for clinical decisions based on this content.

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