From the Research
Keppra (levetiracetam) for dogs is typically dosed at 20-60 mg/kg given orally every 8-12 hours, with most veterinarians starting at around 20-30 mg/kg twice daily. The medication comes in various strengths including 250 mg, 500 mg, and 1000 mg tablets, as well as a liquid formulation (100 mg/ml) which can be helpful for smaller dogs. Dosing should always be determined by a veterinarian based on the dog's specific condition, weight, and response to treatment. Keppra is used primarily to control seizures in dogs with epilepsy, either as a sole medication or in combination with other anticonvulsants like phenobarbital. It's generally well-tolerated with fewer side effects than some other seizure medications, though some dogs may experience sedation, decreased appetite, or gastrointestinal upset. The drug works by modulating neurotransmitter release in the brain, helping to prevent the abnormal electrical activity that causes seizures. Blood monitoring is typically not required for Keppra as it is for some other anticonvulsants, making it a convenient option for long-term seizure management. Never discontinue Keppra suddenly as this could trigger severe seizures; any dosage changes should be supervised by a veterinarian. Some key points to consider when using Keppra for dogs include:
- The importance of gradual dosage adjustments to minimize the risk of adverse effects 1
- The potential for Keppra to be used in combination with other anticonvulsants, such as phenobarbital, to achieve optimal seizure control 2
- The need for regular monitoring of the dog's condition and adjustment of the dosage as needed to ensure the best possible outcome 3
- The potential for Keppra to be a cost-effective option for long-term seizure management, particularly when compared to other anticonvulsants 4
- The importance of considering the individual dog's needs and response to treatment when determining the optimal dosage and treatment plan 5