FreeStyle Libre 3 Sensor Replacement Schedule
FreeStyle Libre 3 sensors should be changed every 14 days, as this is the maximum approved wear duration for the device. 1, 2, 3
Sensor Wear Duration
- The FreeStyle Libre 3 is designed as a 14-day continuous glucose monitoring system, meaning each sensor must be replaced after 14 days of wear 3
- This 14-day replacement schedule is consistent across the FreeStyle Libre product line (including Libre 2 and Libre 3) 4, 1
- The sensor measures interstitial glucose continuously throughout this entire 14-day period 4, 1
Accuracy Considerations Across Sensor Lifespan
- The FreeStyle Libre 3 maintains stable accuracy throughout the full 14-day wear period, with an overall mean absolute relative difference (MARD) of 7.8% 3
- Research on earlier FreeStyle Libre models showed that accuracy was lowest during the first day (MARD 14.5%) and last day (MARD 14.7%) of wear, with best performance during days 5-7 (MARD 7.8%) 5
- However, the third-generation FreeStyle Libre 3 demonstrates improved and stable performance across all 14 days, with 93.4% of readings within ±20% or ±20 mg/dL of reference values 3
Best Practices for Sensor Changes
- Insert the new sensor before removing the old one to avoid gaps in continuous glucose monitoring data 1, 2
- Patients should have uninterrupted access to sensor supplies to minimize gaps in monitoring 4, 1
- The device should be scanned at minimum once every 8 hours to capture complete 24-hour glucose data 4, 1
Critical Pitfalls to Avoid
- Do not extend sensor wear beyond 14 days, as this may compromise accuracy and is outside the approved use parameters 2
- Inconsistent sensor use or allowing gaps between sensors reduces clinical benefit and limits the technology's ability to improve glycemic control 1
- Assess for skin reactions (irritation or allergy) at insertion sites, as these can interfere with successful long-term device use 4