What preoperative evaluation is needed prior to breast reduction surgery?

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Preoperative Evaluation for Breast Reduction Surgery

For breast reduction surgery, obtain a thorough history focusing on cardiovascular risk factors, bleeding disorders, and medications; perform a focused physical examination; and order preoperative mammography for women ≥40 years or those with breast cancer risk factors, while reserving laboratory testing for patients with specific comorbidities rather than ordering routine panels. 1, 2, 3

Essential History Components

Document the following specific elements:

  • Cardiovascular risk factors including hypertension, diabetes, coronary disease, heart failure, and functional capacity (ability to climb ≥2 flights of stairs indicates ≥4 METs and generally allows proceeding without cardiac testing) 1, 2
  • Bleeding history including personal or family history of bleeding disorders, easy bruising, or prolonged bleeding from minor procedures 1, 2
  • Current medications particularly anticoagulants, antiplatelet agents, diuretics, ACE inhibitors, ARBs, NSAIDs, and any medications affecting coagulation or electrolytes 1, 2
  • Tobacco use as this significantly impacts wound healing and complication rates in breast surgery 3, 4
  • Family history of breast or ovarian cancer to guide mammography decisions 3
  • Prior breast surgery or biopsies which increase the likelihood of occult pathology 3
  • Comorbidities including renal disease, liver disease, hematologic disorders, and diabetes 1, 2

Physical Examination

Perform a focused examination assessing:

  • Breast anatomy including size, symmetry, skin quality, nipple-areolar complex position, and presence of masses or skin changes 4
  • Cardiovascular examination for signs of heart failure, arrhythmias, or valvular disease 1, 2
  • Signs of anemia such as pallor or tachycardia 2

Imaging: Mammography

Preoperative mammography is indicated for:

  • All women ≥40 years of age undergoing breast reduction, as 1.3% have high-risk lesions and 0.3% have occult malignancy in reduction specimens 3
  • Women <40 years with risk factors including family history of breast cancer, prior breast biopsy, or prior breast surgery 3
  • The rationale: Discovery of malignancy or high-risk lesions in the surgical specimen may preclude breast-conserving surgery options, making preoperative detection critical 3

Common pitfall: Many plastic surgeons do not routinely order mammography, but the discovery of invasive cancer in reduction specimens can significantly alter surgical management and oncologic outcomes 3

Laboratory Testing: Risk-Stratified Approach

The key principle: Order tests only when results would change perioperative management, not routinely for all patients. 1, 2

Complete Blood Count (CBC)

Obtain CBC for:

  • Patients with history of anemia or recent blood loss 2
  • Patients with diseases increasing anemia risk including liver disease or hematologic disorders 2
  • When significant blood loss is anticipated (breast reduction typically involves moderate blood loss) 2

Electrolytes and Renal Function

Obtain electrolytes and creatinine for:

  • Patients taking medications affecting electrolytes including diuretics, ACE inhibitors, ARBs, NSAIDs, or digoxin 1, 2
  • Patients with hypertension, heart failure, chronic kidney disease, complicated diabetes, or liver disease 2

Do not order for healthy patients without these conditions 1, 2

Glucose Testing

Obtain random glucose for:

  • Patients at high risk of undiagnosed diabetes (obesity, family history, metabolic syndrome) 1, 2
  • Patients with known diabetes only if A1C results would change perioperative management 1, 2

The incidence of occult diabetes in presurgical populations is only 0.5%, making universal screening unjustified 2

Coagulation Studies

Obtain PT/aPTT/INR for:

  • Patients with history of bleeding disorders or abnormal bleeding 1, 2
  • Patients with liver disease or other conditions predisposing to coagulopathy 1, 2
  • Patients taking anticoagulants 1, 2

Do not order for patients without these risk factors, as inherited coagulopathies have low prevalence and indiscriminate testing is not warranted 2

Urinalysis

Not indicated for breast reduction surgery unless the patient has urologic symptoms, as urinalysis is only recommended for urologic procedures or implantation of foreign material 1, 2

Electrocardiography (ECG)

Obtain preoperative ECG for:

  • Patients with signs or symptoms of cardiovascular disease (chest pain, dyspnea, palpitations, syncope) 1, 2
  • Patients undergoing intermediate-risk surgery with cardiovascular risk factors (coronary disease, structural heart disease, heart failure, cerebrovascular disease, diabetes, or renal impairment) - breast reduction falls into this category 1, 2
  • Patients with poor functional capacity (<4 METs or unable to climb 2 flights of stairs) 2

Do not obtain for asymptomatic patients without cardiovascular risk factors undergoing low-risk procedures 1, 2

Chest Radiography

Not routinely indicated for asymptomatic patients 1, 2

Obtain only for:

  • Patients with new or unstable cardiopulmonary signs or symptoms 1, 2
  • Patients at risk of postoperative pulmonary complications if results would change management 1, 2

Special Consideration: Pregnancy Testing

Consider pregnancy testing for all women of childbearing age, as history and physical examination may be insufficient to identify early pregnancy 2

What NOT to Do

Avoid these common errors:

  • Do not order routine test panels "just to be safe" or because "it's always been done" 2
  • Do not use arbitrary age cutoffs as the sole indication for testing 2
  • Do not order tests that will not alter perioperative care 2
  • Do not skip mammography discussion in women ≥40 or those with risk factors, as this represents a critical opportunity to detect occult malignancy 3

References

Guideline

Guideline Directed Topic Overview

Dr.Oracle Medical Advisory Board & Editors, 2025

Guideline

Preoperative Screening Guidelines

Praxis Medical Insights: Practical Summaries of Clinical Guidelines, 2025

Professional Medical Disclaimer

This information is intended for healthcare professionals. Any medical decision-making should rely on clinical judgment and independently verified information. The content provided herein does not replace professional discretion and should be considered supplementary to established clinical guidelines. Healthcare providers should verify all information against primary literature and current practice standards before application in patient care. Dr.Oracle assumes no liability for clinical decisions based on this content.

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