What is the differential diagnosis (Ddx) for lower back pain (LBP)?

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Differential Diagnosis for Lower Back Pain

The following is a comprehensive differential diagnosis for lower back pain, categorized for clarity and emphasis on critical conditions.

  • Single Most Likely Diagnosis
    • Musculoskeletal Strain: This is the most common cause of lower back pain, often resulting from overuse, heavy lifting, or sudden awkward movements. The justification for this being the single most likely diagnosis is its high prevalence and the common activities that lead to it.
  • Other Likely Diagnoses
    • Herniated Disc: A condition where the soft inner gel of the disc leaks out through a tear or crack in the outer layer, potentially irritating nearby nerves and causing pain. This is a common issue, especially in individuals with a history of heavy lifting or those who are overweight.
    • Degenerative Disc Disease: A condition where the spinal discs lose their cushioning ability, leading to pain and stiffness. This condition is more common with aging and can be exacerbated by smoking, obesity, and genetic factors.
    • Spondylosis: A defect in the pars interarticularis, the thin piece of bone that connects the superior and inferior articular facets of the spine. This can lead to spondylolisthesis, where a vertebra slips out of place.
  • Do Not Miss Diagnoses
    • Cauda Equina Syndrome: A serious condition that occurs when the nerves in the spinal canal are compressed, leading to loss of bladder and bowel control, among other symptoms. It requires immediate medical attention.
    • Spinal Infection (e.g., Osteomyelitis, Discitis): Infections of the spine can cause severe back pain and are medical emergencies, especially if they lead to abscess formation or sepsis.
    • Spinal Fracture: Especially in individuals with osteoporosis or those who have experienced trauma, a spinal fracture can cause sudden and severe back pain.
    • Cancer: Metastatic cancer to the spine or primary spinal tumors can cause back pain, often with other systemic symptoms like weight loss or fever.
  • Rare Diagnoses
    • Ankylosing Spondylitis: A form of arthritis that primarily affects the spine, although it can also affect other joints. It leads to severe, chronic pain and discomfort.
    • Spondyloarthritis: A group of inflammatory diseases that can cause pain and stiffness in the spine, as well as other parts of the body.
    • Paget's Disease of the Bone: A condition that affects bone remodeling, leading to bones becoming weakened and deformed. It can cause back pain if the spine is involved.

Each of these diagnoses has a distinct set of symptoms and risk factors, and a thorough medical history, physical examination, and sometimes imaging studies are necessary to determine the underlying cause of lower back pain.

Professional Medical Disclaimer

This information is intended for healthcare professionals. Any medical decision-making should rely on clinical judgment and independently verified information. The content provided herein does not replace professional discretion and should be considered supplementary to established clinical guidelines. Healthcare providers should verify all information against primary literature and current practice standards before application in patient care. Dr.Oracle assumes no liability for clinical decisions based on this content.

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