What is the approach to detecting and managing bladder and ureter injuries during or after general surgery?

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Last updated: December 18, 2025View editorial policy

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Detection of Bladder and Ureter Injuries During General Surgery

Direct inspection of the ureter and bladder should always be performed during emergency laparotomy when injury is suspected, with intraoperative use of methylene blue or indigo carmine (40 mg IV) to enhance detection of urinary tract injuries. 1

Intraoperative Detection Strategies

For Suspected Ureteral Injuries

  • Maintain high clinical suspicion in high-energy blunt trauma with deceleration mechanisms, multi-system involvement, and all penetrating abdominal trauma 1

  • Direct visual inspection of the ureter is mandatory during any emergency laparotomy when ureteral injury is suspected 1

  • Administer indigo carmine (40 mg IV) by slow intravenous infusion to visualize urine leakage intraoperatively; a second 40 mg dose can be given 20-30 minutes after the first if needed 1

    • Contraindications: hemodynamic instability or creatinine clearance <10 mL/min 1
    • Rare adverse events include severe hypotension, hypoxia, and cardiac arrest 1
  • Intravenous urography may be useful in unstable patients during surgery when CT scanning is not available and urinary tract injury is suspected 1

For Suspected Bladder Injuries

  • Retrograde cystography (conventional radiography or CT-scan) is the gold standard for bladder injury detection, superior to IV contrast-enhanced CT with delayed phase 1

  • Direct inspection of the intraperitoneal bladder should always be performed during emergency laparotomy whenever feasible 1

  • Inject dyed saline solution (methylene blue or indigo carmine) via an indwelling urinary catheter to improve detection rates of bladder defects 1

    • This technique is particularly useful for dome injuries that may not be immediately visible 1

Postoperative Detection

Clinical Indicators

  • Gross hematuria and abdominal tenderness are the most common presenting symptoms of missed bladder injuries 1

  • For ureteral injuries, suspect delayed diagnosis when patients develop fever, flank pain, decreased renal function, or signs of peritonitis 1, 2

  • Biochemical markers can aid diagnosis: increased serum inflammatory markers (C-RP), decreased renal function, increased peritoneal fluid creatinine and urea, or altered serum-to-peritoneal fluid creatinine ratio 1

Imaging Approach

  • CT urography with both nephrographic and excretory phases is the gold standard for postoperative diagnosis of iatrogenic urinary tract injuries 1

  • For ureteral injuries specifically, intravenous contrast-enhanced CT scan with delayed phase should be performed in hemodynamically stable patients 1

  • For bladder injuries, CT cystography with bladder distention using >300 mL of diluted contrast media has 85-100% accuracy 1

Critical Timing Considerations

Prompt identification is paramount: Delayed diagnosis of ureteral injury correlates directly with unsuccessful repair and increased morbidity 2. Only 17.6% of iatrogenic ureteral injuries are identified during primary surgery, yet immediate repair when detected intraoperatively achieves good results 1.

Ureteral injuries diagnosed postoperatively should be treated as soon as possible to avoid complications and sepsis 1

Common Pitfalls to Avoid

  • Thermal injuries are more subtle than direct transection and harder to recognize, leading to delayed diagnosis 1

  • Do not rely solely on IV contrast-enhanced CT with delayed phase for bladder injuries—it is less sensitive and specific than retrograde cystography 1

  • In pelvic bleeding requiring angioembolization, postpone cystography until after the angiographic procedure to avoid affecting angiography accuracy 1

  • Failing to inspect the ureter during laparotomy in penetrating abdominal trauma or high-energy blunt trauma is a critical error 1

Classification and Documentation

Once identified, classify injuries using the American Association for the Surgery of Trauma (AAST) organ-specific injury scoring scale 1. For bladder injuries, also document anatomical classification (extraperitoneal, intraperitoneal, or combined) 1.

References

Guideline

Guideline Directed Topic Overview

Dr.Oracle Medical Advisory Board & Editors, 2025

Research

[Iatrogenic Injuries of Urinary Tract : Outcomes of Surgical Repairs].

Hinyokika kiyo. Acta urologica Japonica, 2018

Professional Medical Disclaimer

This information is intended for healthcare professionals. Any medical decision-making should rely on clinical judgment and independently verified information. The content provided herein does not replace professional discretion and should be considered supplementary to established clinical guidelines. Healthcare providers should verify all information against primary literature and current practice standards before application in patient care. Dr.Oracle assumes no liability for clinical decisions based on this content.

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